65739-05-1

Basic information

• Product Name: Benzene, 1-bromo-4-(2,2,2-trichloroethyl)-
• CAS NO: 65739-05-1
• Molecular Formula: C8H6BrCl3
• Molecular Weight: 288.399
• Mol File: 65739-05-1.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-(2,2,2-trichloroethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-(2,2,2-trichloroethyl)-(65739-05-1)
• EPA Substance Registry System: Benzene, 1-bromo-4-(2,2,2-trichloroethyl)-(65739-05-1)

Safety Data

• Hazardous Substances Data: 65739-05-1(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 75-35-4 1,1-Dichloroethylene 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 1190230-36-4 (E)-2-(4-bromobenzylidene)-1-(5-(tert-butyldiphenylsilyloxy)pentyl)cyclobutanol 

Relevant articles and documents

A phenylacetic acid compound preparation method (by machine translation)

The invention relates to the field of chemical synthesis, in particular relates to a preparation method of the compound of phenylacetic acid. The present invention provides a preparation method of the compound of phenylacetic acid, the acid compounds of the structural formula states the benzene second grade shown in formula I, the preparation method comprises the following steps: (1) diazo addition reaction: formula II compound containing vinylidene chloride, acid, diazotization reagent, phase transfer catalyst and a copper catalyst in the system of the formula III compound: (2) hydrolysis reaction: the compound of formula III in the presence of acid hydrolysis of formula I compounds. The present invention provides a preparation method of and is simple, easy operation, low cost of raw materials, mild reaction conditions, low risk, does not need to use expensive noble metal catalyst and complex industrial operation means, the product quality is stable, therefore easy achievement of large-scale industrial production. (by machine translation)

Cascade synthesis of (E)-2-alkylidenecyclobutanols

A facile, one-pot reaction cascade condenses 1,1,1-trichloroalkanes with α,β-unsaturated ketones to unexpectedly furnish moderate to good yields of (E)-2-alkylidenecyclobutanols.