69213-38-3Relevant articles and documents
5-Tetrazolecarboxamides and Their Salts: New Orally Active AntiAllergy Agents
Klaubert, Dieter H.,Sellstedt, John H.,Guinosso, Charles J.,Bell, Stanley C.,Capetola, Robert J.
, p. 748 - 752 (2007/10/02)
A new series of orally active antiallergy agents, tetrazole-5-carboxamides, has been prepared by acylation of substituted anilines or aminopyridines with 1-benzyl- or 4-(methoxybenzyl)-5-tetrazolecarbonyl chloride and subsequent removal of the benzyl subs
Tetrazole-5-carboxamide derivatives
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, (2008/06/13)
Anti-allergic agents of N-aromatic 1H-(or 2H) tetrazole-5-carboxamide derivation present the following formulae: STR1 in which R1 is --CN or --CONH2 ; R2 is hydrogen, lower alkyl, lower alkoxy, halo, polyhalo(lower)alkyl, lower alkyl carbonyl or carb(lower)alkoxy; X is --CH2 --, --O--, or STR2 where R3 is lower alkyl; and R4 is hydrogen or lower alkyl; or a pharmaceutically acceptable salt thereof.