6974-31-8

Basic information

• Product Name: 11-(acetylsulfanyl)undecanoic acid
• CAS NO: 6974-31-8
• Molecular Formula: C₁₃H₂₄O₃S
• Molecular Weight: 260.3929
• Mol File: 6974-31-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 393.4°C at 760 mmHg
• Flash Point: 191.7°C
• Density: 1.046g/cm³
• Vapor Pressure: 2.77E-07mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: 11-(acetylsulfanyl)undecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 11-(acetylsulfanyl)undecanoic acid(6974-31-8)
• EPA Substance Registry System: 11-(acetylsulfanyl)undecanoic acid(6974-31-8)

Safety Data

• Hazardous Substances Data: 6974-31-8(Hazardous Substances Data)

Usage

Derivative of

Undecanoic acid

Attached groups

Acetyl group and sulfanyl group

Attachment position

11th carbon atom

Common use

Synthesis of other organic compounds

Potential applications

Pharmaceutical and chemical industries

Research and development

Subject of interest for further study

Chemical structure

A long-chain carboxylic acid with an acetylsulfanyl functional group at the 11th carbon position

Functional groups

Carboxylic acid, acetyl, and sulfanyl

Physical state

Likely a solid at room temperature due to its long-chain structure

Solubility

May be soluble in organic solvents such as ethanol or acetone, but insoluble in water due to its hydrophobic nature

Stability

Relatively stable under normal conditions, but sensitive to heat, light, and strong bases or acids

Reactivity

Can undergo reactions such as esterification, amidation, and substitution due to the presence of functional groups

Analytical techniques

Can be identified and characterized using techniques like infrared spectroscopy (IR), nuclear magnetic resonance (NMR), and mass spectrometry (MS)

Upstream product

• 2834-05-1 11-bromoundecanoic acid 
• 10387-40-3 potassium thioacetate 
• 71310-21-9 11-mercaptounadecanoic acid 
• 108-24-7 acetic anhydride 
• 1611-56-9 1-Bromo-11-hydroxyundecane 
• 765-04-8 undecane-1,11-diol 
• 13688-67-0 1,10-undecadiene 
• 75-36-5 acetyl chloride 
• 507-09-5 tiolacetic acid 
• 112-38-9 10-undecenoic acid 
• 507-09-5 thioacetic acid 

Downstream Products

• 64-17-5 ethanol 
• 71310-21-9 11-mercaptounadecanoic acid 
• 1453813-97-2 S-(11-((4-(3-methyl-3-((2-nitrobenzyl)oxy)but-1-yn-1-yl)phenyl)amino)-11-oxoundecyl)ethanethioate 

Relevant articles and documents

Multivalent interaction and selectivities in selectin binding of functionalized gold colloids decorated with carbohydrate mimetics

Colloidal gold particles with functionalized organic shells were applied as novel selectin binders. The ligand shell was terminated with different monocyclic carbohydrate mimetics as simplified analogs of the sLex unit found in biological selectin ligands. The multivalent presentation of the sulfated selectin binding epitopes on the gold particles led to extremely high binding affinities towards L- and P-selectin and IC50 values in the subnanomolar range. Depending on the ring size of the sulfated carbohydrate mimetic, its substitution pattern and its configuration, different selectivities for either L-selectin or P-selectin were obtained. These selectivities were not found for gold particles with simple acyclic sulfated alcohols, diols and triols in the ligand shell. In addition, the influence of the particle size and the thickness of the hydrophobic organic shell were systematically investigated.

Gold nanoparticles functionalised with fast water exchanging Gd3+ chelates: Linker effects on the relaxivity

The relaxivity displayed by Gd3+ chelates immobilized onto gold nanoparticles is the result of the complex interplay between the nanoparticle size, the water exchange rate and the chelate structure. In this work we study the effect of the length of ω-thioalkyl linkers, anchoring fast water exchanging Gd3+ chelates onto gold nanoparticles, on the relaxivity of the immobilized chelates. Gold nanoparticles functionalized with Gd3+ chelates of mercaptoundecanoyl and lipoyl amide conjugates of the DO3A-N-(α-amino)propionate chelator were prepared and studied as potential CA for MRI. High relaxivities per chelate, of the order of magnitude 28-38 mM-1 s-1 (30 MHz, 25 °C), were attained thanks to simultaneous optimization of the rotational correlation time and of the water exchange rate. Fast local rotational motions of the immobilized chelates around connecting linkers (internal flexibility) still limit the attainable relaxivity. The degree of internal flexibility of the immobilized chelates seems not to be correlated with the length of the connecting linkers. Biodistribution and MRI studies in mice suggest that the in vivo behavior of the gold nanoparticles was determined mainly by size. Small nanoparticles (HD = 3.9 nm) undergo fast renal clearance and avoidance of the RES organs while larger nanoparticles (HD = 4.8 nm) undergo predominantly hepatobiliary excretion. High relaxivities, allied to chelate and nanoparticle stability and fast renal clearance in vivo suggest that functionalized gold nanoparticles hold great potential for further investigation as MRI contrast agents. This study contributes to a better understanding of the effect of linker length on the relaxivity of gold nanoparticles functionalized with Gd3+ complexes. It is a relevant contribution towards design rules for nanostructures functionalized with Gd3+ chelates as Contrast Agents for MRI and multimodal imaging. This journal is

Visualization of latent fingermarks by nanotechnology: Reversed development on paper-a remedy to the variation in sweat composition

Don't sweat it: Negative fingermarks are developed on paper by the application of gold nanoparticles (gold circles) that are capped by a bifunctional ligand, and then silver precipitation. In this process, paper is the substrate and the fingermarks serve as a mask. This approach may contribute to the successful recovery of latent fingermarks by law enforcement agencies. Copyright