Welcome to LookChem.com Sign In|Join Free

CAS

  • or

70110-25-7

Post Buying Request

70110-25-7 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

70110-25-7 Usage

Description

(R)-2-Chloropropionyl chloride, with the molecular formula C3H4Cl2O, is a colorless to light yellow liquid characterized by a pungent odor. It is a chemical compound that serves as a crucial intermediate in the synthesis of various products, particularly in the pharmaceutical and agrochemical industries. Its versatility in the chemical industry is underscored by its use in the production of fine chemicals and pharmaceutical intermediates, making it an essential component in the development of new and existing compounds.

Uses

Used in Pharmaceutical Industry:
(R)-2-Chloropropionyl chloride is used as a key intermediate for the synthesis of various pharmaceuticals. Its reactivity and functional group compatibility make it suitable for the development of new drugs and the improvement of existing ones. It plays a critical role in the production of medications that address a wide range of health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-2-Chloropropionyl chloride is utilized as an intermediate in the creation of pesticides and other crop protection agents. Its involvement in the synthesis of these products contributes to the development of more effective and targeted solutions for agricultural challenges.
Used in Synthesis of Fine Chemicals:
(R)-2-Chloropropionyl chloride is used as a reagent in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including research, diagnostics, and specialty manufacturing. Its ability to participate in a variety of chemical reactions makes it a valuable asset in the production of these high-quality compounds.
Used in Production of Pharmaceutical Intermediates:
As a precursor in the production of pharmaceutical intermediates, (R)-2-Chloropropionyl chloride is instrumental in the development of the building blocks for new pharmaceuticals. These intermediates are essential for the synthesis of active pharmaceutical ingredients, which are the key components of medications.
It is important to handle (R)-2-Chloropropionyl chloride with care due to its potential hazards if not used properly, ensuring safety in the chemical industry and the integrity of the products it helps to create.

Check Digit Verification of cas no

The CAS Registry Mumber 70110-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,1,1 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 70110-25:
(7*7)+(6*0)+(5*1)+(4*1)+(3*0)+(2*2)+(1*5)=67
67 % 10 = 7
So 70110-25-7 is a valid CAS Registry Number.

70110-25-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name R-(-)-2-Chloropropionyl Chloride

1.2 Other means of identification

Product number -
Other names Propanoyl chloride, 2-chloro-, (R)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70110-25-7 SDS

70110-25-7Relevant articles and documents

Preparation method of D-2-chloropropionyl chloride and D-2-chloropropionyl chloride

-

Paragraph 0055; 0060-0065; 0070-0076; 0081-0086; 0101-0114, (2021/03/13)

The invention is applicable to the technical field of synthesis of medical intermediates, and provides a preparation method of D-2-chloropropionyl chloride and D-2-chloropropionyl chloride, the preparation method comprises the following steps: adding L-ethyl lactate and a catalyst into a reaction vessel, dropwisely adding thionyl chloride at -10-10 DEG C, heating to 65-70 DEG C, and carrying out heat preservation reaction; after the reaction is finished, cooling to 10-30 DEG C, and carrying out reduced pressure concentration and other treatment to obtain ethyl D-2-chloropropionate; adding resin, anhydrous formic acid and water, heating to 70-100 DEG C, and reacting for 2-5 hours; after the reaction is finished, cooling to 10-30 DEG C, filtering, and distilling to obtain D-2-chloropropionicacid; and dropwise adding thionyl chloride at 0-5 DEG C, heating to 45-65 DEG C, carrying out heat preservation reaction, and carrying out vacuum concentration and distillation treatment to obtain the product. The method realizes 10kg-grade large-scale production of D-2-chloropropionyl chloride, and has the advantages of high yield, high purity, recyclable catalyst, and no need of rectification equipment.

Production process of chloropropionyl glutamine

-

Paragraph 0023-0026; 0030-0033; 0035, (2020/03/09)

The invention relates to the technical field of chemical engineering, and discloses a production process of chloropropionyl glutamine. The production process comprises following steps: carrying out acylating chlorination reaction: adopting D-2-chloropropionic acid and thionyl chloride as raw materials, adopting DMF (N, N-dimethylformamide) as a catalyst, and carrying out reaction to generate D-2-chloropropionyl chloride, sulfur dioxide and hydrogen chloride. According to the production process of chloropropionyl glutamine, 791kg of thionyl chloride is pressed into a dry and clean 2000 L enamelreaction kettle by using nitrogen, stirring is started, and 0.75kg of N, N-dimethylformamide is slowly dropwise added; then, 600kg of D-2-chloropropionic acid is pressed into a dry and clean 1000L enamel high-level tank by using nitrogen gas, a reaction kettle jacket is subjected to 75 DEG C hot water bath to increase the temperature of the system to 60-65 DEG C, D-2-chloropropionic acid is dropwise added into the reaction kettle for about 4 h at 60 to 65 DEG C, and the gas release amount is controlled by adjusting the dropwise adding speed. T production process is simple in steps, complete in reactant reaction, high in raw material utilization rate and low in preparation cost, troubles of users are avoided, and the production process is convenient for users to use.

PROCESS FOR PREPARING 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES THEREOF

-

Paragraph 0405-0407; 0444; 0445; 0622-0626; 0632-0634, (2020/07/23)

The present invention provides processes for preparing 7H-pyrrolo[2,3-d]pyrimidine derivatives, which are useful as a Janus kinase (JAK) inhibitor, intermediates thereof, and processes for preparing the intermediates. The present invention provides processes for preparing 3-[(3S, 4R)-3-methyl-6-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,6-diazaspiro[3.4]octan-1-yl]-3-oxopropanenitrile using salts of (3S,4R)-1-benzyl-3-methyl-1,6-diazaspiro[3.4]octane with organic acids.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 70110-25-7