76115-06-5Relevant articles and documents
Preparation and properties of organo-soluble tetraphenylethylene monolayer-protected gold nanorods
Cao, Tiantian,Li, Dengfeng,Yao, Xuyang,Xu, Yikai,Ma, Xiang
, p. 1 - 5 (2016)
Organo-soluble tetraphenylethylene derived monolayer-protected gold nanorods were prepared and characterized. The prepared gold nanorods covered with tetraphenylethylene thiol via the strong covalent Au-S linkage were found to be soluble and stable in org
Engineering Sensor Arrays Using Aggregation-Induced Emission Luminogens for Pathogen Identification
Zhou, Chengcheng,Xu, Wenhan,Zhang, Pengbo,Jiang, Meijuan,Chen, Yuncong,Kwok, Ryan T. K.,Lee, Michelle M. S.,Shan, Guogang,Qi, Ruilian,Zhou, Xin,Lam, Jacky W. Y.,Wang, Shu,Tang, Ben Zhong
, (2019)
Lacking rapid and reliable pathogen diagnostic platforms, inadequate or delayed antimicrobial therapy could be made, which greatly threatens human life and accelerates the emergence of antibiotic-resistant pathogens. In this contribution, a series of simple and reliable sensor arrays based on tetraphenylethylene (TPE) derivatives are successfully developed for detection and discrimination of pathogens. Each sensor array consists of three TPE-based aggregation-induced emission luminogens (AIEgens) that bear cationic ammonium group and different hydrophobic substitutions, providing tunable logP (n-octanol/water partition coefficient) values to enable the different multivalent interactions with pathogens. On the basis of the distinctive fluorescence response produced by the diverse interaction of AIEgens with pathogens, these sensor arrays can identify different kinds of pathogens, even normal and drug-resistant bacteria, with nearly 100% accuracy. Furthermore, blends of pathogens can also be identified accurately. The sensor arrays exhibit rapid response (about 0.5 h), high-throughput, and easy-to-operate without washing steps.
Electrospun aggregation-induced emission active POSS-based porous copolymer films for detection of explosives
Zhou, Hui,Ye, Qun,Neo, Wei Teng,Song, Jing,Yan, Hong,Zong, Yun,Tang, Ben Zhong,Hor, T. S. Andy,Xu, Jianwei
, p. 13785 - 13788 (2014)
Electrospun aggregation-induced emission (AIE)-active polyhedral oligomeric silsesquioxane (POSS)-based copolymer films exhibit an approximately 9-fold increase in response to explosive vapors compared to dense films although porous copolymer films have a thickness as high as 560 ± 60 nm. This journal is
Aggregation induced emission based fluorescence pH and temperature sensors: Probing polymer interactions in poly(N-isopropyl acrylamide-co-tetra(phenyl)ethene acrylate)/poly(methacrylic acid) interpenetrating polymer networks
Zhou, Hui,Liu, Feng,Wang, Xiaobai,Yan, Hong,Song, Jing,Ye, Qun,Tang, Ben Zhong,Xu, Jianwei
, p. 5490 - 5498 (2015)
Aggregation induced emission (AIE) active copolymers P1-P6 with high molecular weights (14 000-17 000) and low polydispersity indices (1.3-1.4) were prepared through copolymerization of N-isopropyl acrylamide (NIPAM) and tetra(phenyl)ethene (TPE)-based acrylate monomers. Copolymers P1-P6 show comparable thermal stability to poly(N-isopropylacrylamide) (PNIPAM), while their glass transition temperatures are higher by 7-9 °C than those of pristine PNIPAM. Copolymers P1-P6 are soluble in common organic solvents as well as in water. They retain a similar thermal sensitivity to PNIPAM, but their lower critical solution temperatures (LCST) are reduced with increase of TPE content. By changing the molar ratio of P1-P6/poly(methacrylic acid) (PMAA) and pH, complexes P1-P6-PMMA were studied by fluorescence spectroscopy and dynamic light scattering (DLS). The complexes are non-emissive in THF, and their fluorescence can be turned on upon addition of water. Moreover, their fluorescence is enhanced with the decrease in pH values due to the formation of interpenetrating polymer networks (IPNs) through inter-polymer hydrogen bonding. Fluorescence spectroscopy and DLS results also reveal that the phase transition behaviour of IPNs upon heating could be significantly modified by pH change. Reduction in the pH value from 7.0 to 4.0 leads to the decrease in LSCT of IPNs by up to 5 °C with respect to PNIPAM. By tuning the pH value to dissociate the formed inter-polymer hydrogen bonds, the formed IPNs would be able to fold cooperatively to a compact structure without a loss of solubility at temperatures below the LCST. Thus, these novel IPNs with AIE active moieties would be used as drug delivery systems, in which the release process could be readily monitored by fluorescence spectroscopy.
Aggregation-induced emission based PET probe for liver function imaging
Liu, Song,Huang, Yong,Wu, Renbo,Yang, Zequn,Sun, Yuli,Xiao, Hao,Cheng, Xuebo,Wu, Zehui,Liu, Yajing
, p. 16305 - 16313 (2019)
To locate the site of a liver lesion by positron emission tomography (PET) imaging and then remove the lesion site under the guidance of fluorescence imaging, we designed an aggregate-induced emission (AIE)-based PET probe [nat/68Ga] 5 based on
Aggregation Induced Emission Mediated Controlled Release by Using a Built-In Functionalized Nanocluster with Theranostic Features
Zhou, Zhan,Zhang, Cheng Cheng,Zheng, Yuhui,Wang, Qianming
, p. 410 - 418 (2016)
We report biological evaluation of a novel nanoparticle delivery system based on 1,1,2-triphenyl-2-(p-hydroxyphenyl)-ethene (TPE-OH, compound 1), which has tunable aggregation-induced emission (AIE) characteristics. Compound 1 exhibited no emission in DMS
High Efficiency Luminescent Liquid Crystalline Polymers Based on Aggregation-Induced Emission and "jacketing" Effect: Design, Synthesis, Photophysical Property, and Phase Structure
Guo, Yang,Shi, Dong,Luo, Zhi-Wang,Xu, Jia-Ru,Li, Ming-Li,Yang, Long-Hu,Yu, Zhen-Qiang,Chen, Er-Qiang,Xie, He-Lou
, p. 9607 - 9616 (2017)
A series of high efficiency luminescent liquid crystalline polymers (LLCPs) based on aggregation-induced emission (AIE) and the "Jacketing" effect, namely, poly{2,5-bis{[2-(4-oxytetraphenylethylene)-n-alkyl]oxycarbonyl}styrene} (denoted as Pm, m = 2, 4, 6
Redox-responsive tetraphenylethylene-buried crosslinked vesicles for enhanced drug loading and efficient drug delivery monitoring
Yu, Yunlong,Chen, Yun,Huang, Jingsheng,Wang, Liang,Gu, Zhongwei,Zhang, Shiyong
, p. 7540 - 7547 (2019)
Liposomes have been applied extensively as nanocarriers in the clinic (e.g., to deliver anticancer drugs) due to their biocompatibility and internal cavity structures. However, their low drug-loading capacity (DLC; 10%) and uncontrolled release reduce th
An aggregation-induced emission based turn-on fluorescent chemodosimeter for the selective detection of Pb2+ ions
Khandare, Dipratn G.,Joshi, Hrishikesh,Banerjee, Mainak,Majik, Mahesh S.,Chatterjee, Amrita
, p. 47076 - 47080 (2014)
An aggregation-induced emission (AIE) based turn-on fluorescent chemodosimeter for selective detection of Pb2+ions has been developed by making use of the strong affinity of lead ions for phosphate residues. The probe is a phosphate functionalized tetraphenylethylene derivative and the resulting lead-TPE complex has very low solubility in working solvent and triggers aggregation induced emission. The probe is highly efficient, cost-effective and shows a low detection limit of 10 ppb.
Cationic fluorescent probe based on tetraphenyl ethylene structure
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Paragraph 0068-0072, (2021/05/01)
The invention discloses a cationic fluorescent probe based on a tetraphenyl ethylene structure as shown in a formula I. R1 is selected from H and OH, R2 is selected from what is described in the specification, R3 is selected from H and OH, and R4 is selec
Color tuning and white light emission based on tetraphenylethylene-functionalized cucurbit[7]uril and FRET triggered by host-guest self-assembly
Yang, Jun-Feng,Tao, Zhu,Redshaw, Carl,Zeng, Xi,Luo, Hen
supporting information, (2021/10/29)
This work utilizes the advantages produced when combining aggregation-induced emission in aqueous medium with macrocyclic amphiphiles that can noncovalently incorporate donor/acceptor pairs. A novel FRET system was assembled by using tetraphenylethylene-f