79950-36-0

Basic information

• Product Name: 3-Piperidinepropanoic acid, 3-phenyl-, methyl ester
• CAS NO: 79950-36-0
• Molecular Formula: C15H21NO2
• Molecular Weight: 247.337
• Mol File: 79950-36-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Piperidinepropanoic acid, 3-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Piperidinepropanoic acid, 3-phenyl-, methyl ester(79950-36-0)
• EPA Substance Registry System: 3-Piperidinepropanoic acid, 3-phenyl-, methyl ester(79950-36-0)

Safety Data

• Hazardous Substances Data: 79950-36-0(Hazardous Substances Data)

Upstream product

• 95062-69-4 4-(Acetylamino-methyl)-4-phenyl-heptanedioic acid dimethyl ester 
• 95062-70-7 6-oxo-3-phenylpiperidine-3-propanoic acid methyl ester 
• 79950-35-9 6-oxo-3-phenylpiperidine-3-propanoic acid 
• 38289-18-8 dimethyl 4-cyano-4-phenylheptanedioate 
• 95062-71-8 methyl 3-phenyl-6-thioxopiperidine-3-propionate 
• 186581-53-3 diazomethane 

Downstream Products

• 1104489-64-6 C₂₂H₂₅ClN₂O₃ 
• 79950-38-2 5-phenyl-1-azabicyclo<3.3.1>nonan-2-one 

Relevant articles and documents

Conformation of 5-Phenyl-1-azabicyclononan-2-one, a Bridgehead Amide

The 1H n.m.r. spectrum of 5-phenyl-1-azabicyclononan-2-one reveals W-coupling between only one of the C(9) protons and the equatorial protons on C(6) and C(8), from which it is concluded that the lactam ring has the boat conformation.

Bredt's Rule. Part 6. The Synthesis of 5-Phenyl-1-azabicyclononan-2-one, a Bridgehead Amide

6-Oxo-3-phenylpiperidine-3-propanoic acid, prepared from dimethyl 4-cyano-4-phenylheptanedioate, has been reduced selectively to the corresponding amine and then cyclised thermally or via its acid chloride to 5-phenyl-1-azabicyclononan-2-one.