84863-81-0Relevant articles and documents
The actual active species of sulfur-modified gold-supported palladium as a highly effective palladium reservoir in the suzuki-miyaura coupling
Hoshiya, Naoyuki,Shuto, Satoshi,Arisawa, Mitsuhiro
supporting information; experimental part, p. 743 - 748 (2011/05/06)
The actual active species of the recently developed sulfur-modified, gold-supported palladium material, S-modified Au-supported Pd (SAPd), with one of the lowest Pd-releasing levels and high recyclability in the Suzuki-Miyaura coupling, was investigated. Also, SAPd was found to work repeatedly as an excellent Pd reservoir for liquid-phase combinatorial synthesis. Copyright
Heterocyclic derivatives
-
, (2008/06/13)
Compounds of formula (I) wherein R1 is hydrogen or hydroxy; R2 is hydrogen; or R1 and R2 are joined together so that CR1 14 CR2 is a double bond; X is selected from --Ch2 CH
Design of Inhibitors from the Three-Dimensional Structure of Alcohol Dehydrogenase. Chemical Synthesis and Enzymatic Properties
Freudenreich, Charles,Samama, Jean-Pierre,Biellmann, Jean-Francois
, p. 3344 - 3353 (2007/10/02)
Inhibitors of liver alcohol dehydrogenase were designed from the three-dimensional structure of the enzyme.The ligand to the catalytic zinc ion is an amide group or, better, a formamide group.With the latter function, a hydrogen bond between the NH group and the hydroxyl group of Ser-48 may be formed.The hydrophobic substrate binding site brings structural restraints. α-ω bifunctional molecules show good inhibitory properties possibly due to the interactions with polar residues at the entrance of the substrate binding site.