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4-bromo-2-chloro-1-nitrobenzene is a nitrobenzene derivative that features a benzene ring with a bromine and a chlorine atom attached, along with a nitro group. This chemical is recognized for its role as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also noted for its potential toxicity and harmful effects if ingested, inhaled, or in contact with the skin, necessitating careful handling and disposal to mitigate environmental and health risks.

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  • 89465-97-4 Structure
  • Basic information

    1. Product Name: 4-bromo-2-chloro-1-nitrobenzene
    2. Synonyms: 4-bromo-2-chloro-1-nitrobenzene
    3. CAS NO:89465-97-4
    4. Molecular Formula: C6H3BrClNO2
    5. Molecular Weight: 236.45052
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 89465-97-4.mol
  • Chemical Properties

    1. Melting Point: 42.4 °C
    2. Boiling Point: 286.1±20.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.827±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-bromo-2-chloro-1-nitrobenzene(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-bromo-2-chloro-1-nitrobenzene(89465-97-4)
    11. EPA Substance Registry System: 4-bromo-2-chloro-1-nitrobenzene(89465-97-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 89465-97-4(Hazardous Substances Data)

89465-97-4 Usage

Uses

Used in Pharmaceutical Industry:
4-bromo-2-chloro-1-nitrobenzene is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new medications due to its unique molecular structure and reactivity.
Used in Dye Industry:
In the dye industry, 4-bromo-2-chloro-1-nitrobenzene is utilized as a precursor in the production of dyes, where its specific chemical properties allow for the creation of a range of colorants for different applications.
Used in Organic Compounds Synthesis:
4-bromo-2-chloro-1-nitrobenzene is employed as an intermediate in the synthesis of other organic compounds, highlighting its versatility in organic chemistry and its importance in the preparation of specialty chemicals for various industries.
It is important to handle 4-bromo-2-chloro-1-nitrobenzene with care due to its toxic nature, ensuring that safety guidelines and regulations are strictly followed to minimize the risk of exposure and potential harm to individuals and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 89465-97-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,4,6 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 89465-97:
(7*8)+(6*9)+(5*4)+(4*6)+(3*5)+(2*9)+(1*7)=194
194 % 10 = 4
So 89465-97-4 is a valid CAS Registry Number.

89465-97-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-2-chloro-1-nitrobenzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89465-97-4 SDS

89465-97-4Relevant articles and documents

Discovery of 5-HT6 receptor ligands based on virtual HTS

Tasler, Stefan,Kraus, Jürgen,Wuzik, Andreas,Müller, Oliver,Aschenbrenner, Andrea,Cubero, Elena,Pascual, Rosalia,Quintana-Ruiz, Jordi-Ramon,Dordal, Alberto,Mercè, Ramon,Codony, Xavier

, p. 6224 - 6229 (2008/03/18)

Based on a pharmacophore alignment on a 5-HT6 ligand applying 4SCan technology, a new lead series was identified and further structurally investigated. Kis down to 8 nM were achieved.

Applicability aspects of transition metal-catalyzed aromatic amination protocols in medicinal chemistry

Tasler, Stefan,Mies, Jan,Lang, Martin

, p. 2286 - 2300 (2008/09/19)

The application of palladium- and coppercatalyzed reactions for the aromatic amination of pharmacologically relevant scaffolds is investigated. The focus is set on the scope of several protocols for the introduction of amines of broad structural diversity, allowing for the synthesis of numerous derivatives of one biological hit structure for screening in biological assay systems. Thus, attaining optimized yields and TONs had not a major priority, most important were practical aspects, that is no further purification and drying of reagents and solvents had to be envisaged, ideally only a few transition metalbased protocols had to be applied for synthesizing structurally diverse compounds in sufficient amounts (several milligrams) for screening without any finetuning of conditions and catalytic systems.

Novel cinnamic amides

-

Page/Page column 9, (2008/06/13)

E-cinnamic amides of piperazine derivatives according to formula (I) wherein X is chloro or fluoro and R1 is an aromatic or heteroaromatic group, their pharmaceutically acceptable salts or solvates. The invention also relates to pharmaceutical

Novel bisamidate phosphonate prodrugs

-

, (2008/06/13)

Novel bisamidate phosphonate prodrugs of FBPase inhibitors of the Formula IA: and their use in the treatment of diabetes and other conditions associated with elevated blood glucose.

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