96605-66-2

Basic information

• Product Name: N-Ethyl-N-3-((3-dimethylamino-1-oxo-2-propenyl)phenyl)acetamide
• Synonyms: Zaleplon Related Compound A CIV (15 mg) ((E)-N-(3-[3-(dimethylamino)acryloyl]phenyl)-N-ethylacetamide);N-Ethyl-N-3-[(3-diMethylaMine-1-oxo-2-propene)phen;3-DiMethylaMino-1-(3-N-ethyl-N-acetylaMinophenyl)-2-propen-1-one;N-[3-[3-(DiMethylaMino)-1-oxo-2-propen-1-yl]phenyl]-N-ethyl-acetaMide;Zaleplon related coMpound A;Zaleplon Related CoMpound A CIV;N-[3-[3-(Dimethylamino)acryloyl]phenyl]-N-ethylacetamide;N-[3-[(E)-3-(dimethylamino)prop-2-enoyl]phenyl]-N-ethyl-acetamide
• CAS NO: 96605-66-2
• Molecular Formula: C₁₅H₂₀N₂O₂
• Molecular Weight: 260.33
• EINECS: 1533716-785-6
• Product Categories: Acetics acid and esters;(intermediate of zaleplon);Intermediates of Zaleplon;Amines;Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 96605-66-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 111.0 to 115.0 °C
• Boiling Point: 400.7ºC at 760mmHg
• Flash Point: 168.5ºC
• Appearance: Yellow crystalline powder
• Density: 1.087g/cm3
• Vapor Pressure: 1.25E-06mmHg at 25°C
• Refractive Index: 1.561
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform, Dichloromethane
• PKA: 6.40±0.70(Predicted)
• CAS DataBase Reference: N-Ethyl-N-3-((3-dimethylamino-1-oxo-2-propenyl)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethyl-N-3-((3-dimethylamino-1-oxo-2-propenyl)phenyl)acetamide(96605-66-2)
• EPA Substance Registry System: N-Ethyl-N-3-((3-dimethylamino-1-oxo-2-propenyl)phenyl)acetamide(96605-66-2)

Safety Data

• Hazardous Substances Data: 96605-66-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 96605-66-2 differently. You can refer to the following data:
1. An impurity and intermediate of Zaleplon production
2. An impurity and intermediate of Zaleplon production.It is used as a reagent in the preparation of immunogens for immunodetection and quantification of pyrazolopyrimidine sedatives.

InChI:InChI=1/C15H20N2O2/c1-5-17(12(2)18)14-8-6-7-13(11-14)15(19)9-10-16(3)4/h6-11H,5H2,1-4H3/b10-9+

Upstream product

• 96605-61-7 N-(3-(3-(dimethylamino)acryloyl)phenyl)acetamide 
• 105-58-8 Diethyl carbonate 
• 64-67-5 diethyl sulfate 
• 121-89-1 3-Nitroacetophenone 
• 98-86-2 acetophenone 
• 7463-31-2 3-Acetamidoacetophenone 
• 75-03-6 ethyl iodide 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 200630-96-2 N-(3-acetylphenyl)-N-ethylacetamide 

Downstream Products

• 478081-98-0 N-(3-(3-cyanopyrazolo[1,5-a]pyrimidin-5-yl)phenyl)-N-ethylacetamide 
• 151319-34-5 zaleplon 

Relevant articles and documents

A new method for synthesizing zaleplon (by machine translation)

The present invention provides a new method for synthesizing zaleplon. In particular, the method of the invention takes the acetophenone as raw materials, make N-ethyl-N-[ 3 - (3- dimethyl amine -1-oxo-2-propenyl) phenyl] acetamide, with 3-amino-4-cyano pyrazole reaction, forming N-[ 3 - (3-cyano-pyrazolo [1,5-α] pyrimidin-7-yl) phenyl]-N-ethyl acetamide. The synthetic route of the present invention of fewer steps, after treatment is simple, low cost, suitable for industrial production. (by machine translation)

2-AMINOPHENYL-4-PHENYLPYRIMIDINES AS KINASE INHIBITORS

The present invention relates to compounds of Formula: (I), or pharmaceutically acceptable salt thereof, wherein the variables are defined in the description. The compounds act as kinase inhibitors.