1313516-26-5

• 

• Basic information

  1. Product Name: (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid
  2. Synonyms:
  3. CAS NO:1313516-26-5
  4. Molecular Formula:
  5. Molecular Weight: 272.304
  6. EINECS: N/A
  7. Product Categories: N/A

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: N/A
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid(CAS DataBase Reference)
  10. NIST Chemistry Reference: (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid(1313516-26-5)
  11. EPA Substance Registry System: (S)-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid(1313516-26-5)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1313516-26-5(Hazardous Substances Data)

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1313516-26-5 Usage

Uses

Used in Biomedical Research:
L-ANAP is used as a fluorescent probe for imaging biological processes, allowing researchers to visualize and study cellular and molecular events with high specificity and sensitivity.
Used in Drug Development:
L-ANAP can be incorporated into peptides and proteins to enable the tracking of their distribution, localization, and interactions within biological systems, aiding in the development of targeted drug delivery systems and understanding their mechanisms of action.
Used in Diagnostic Imaging:
The fluorescent properties of L-ANAP make it a valuable tool in diagnostic imaging, where it can be used to label and track specific biological markers or disease indicators, potentially improving the accuracy and efficiency of disease detection and monitoring.
Used in Material Science:
L-ANAP's fluorescent characteristics can also be utilized in the development of advanced materials, such as sensors and optoelectronic devices, where its unique optical properties can contribute to improved performance and functionality.

Check Digit Verification of cas no

The CAS Registry Mumber 1313516-26-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,3,5,1 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1313516-26:
(9*1)+(8*3)+(7*1)+(6*3)+(5*5)+(4*1)+(3*6)+(2*2)+(1*6)=115
115 % 10 = 5
So 1313516-26-5 is a valid CAS Registry Number.

1313516-26-5Upstream product

• 15231-91-1 6-bromo-naphthalen-2-ol 
• 1313516-29-8 N-tert-butoxycarbonyl-6-acetyl-2-naphthylamine 
• 1313516-30-1 L-3-(6-acetyl-2-naphthylamino)-2-aminopropionic acid methyl ester 
• 1590-25-6 1-(6-bromonaphthalen-2-yl)ethanone 
• 10441-41-5 1-(6-hydroxy-2-naphthyl)ethan-1-one 
• 7470-88-4 1-(6-aminonaphthalen-2-yl)ethanone 
• 151600-02-1 6-bromo-2-naphthalenyl trifluoromethanesulfonate 
• 580-13-2 2-bromonaphthalene 

1313516-26-5Downstream Products

1313516-26-5Relevant academic research and scientific papers

Site-specific fluorescence spectrum detection and characterization of hASIC1a channels upon toxin mambalgin-1 binding in live mammalian cells

Wen, Ming,Guo, Xiaoqi,Sun, Peibei,Xiao, Liang,Li, Juan,Xiong, Ying,Bao, Jin,Xue, Tian,Zhang, Longhua,Tian, Changlin

, p. 8153 - 8156 (2015)

The synthesis of fluorescent unnatural amino-acid Anap was optimized and the Anap was incorporated into four sites in an acid-pocket or a transmembrane region of human acid-sensing ion channel-1a (hASIC1a). Combinational Anap fluorescence spectra and patc

Synthetic method of L-3-(6-acethyl-2-naphthylamino)-2-aminopropionic acid

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Paragraph 0008, (2018/01/14)

The invention relates to a synthetic method of L-3-(6-acethyl-2-naphthylamino)-2-aminopropionic acid and mainly solves the technical problem that free L-ANAP (L-3-(6-acethyl-2-naphthylamino)-2-aminopropionic acid) cannot be acquired via the existing synthetic methods. The synthetic method of the invention comprises the steps: in a mixed liquid of methanol and water, hydrolyzing methyl L-3-(6-acethyl-2-naphthylamino)-2-aminopropionate to obtain a lithium salt, acidifying the lithium salt with hydrochloric acid to obtain the target compound L-ANAP. As a gene code and fluorescent non-natural amino acid sensitive to polarity, the L-3-(6-acethyl-2-naphthylamino)-2-aminopropionic acid has unique advantages for the changing process of imaging biology during composition of proteins in organisms.

Enantiospecific synthesis of genetically encodable fluorescent unnatural amino acid l-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid

Xiang, Zheng,Wang, Lei

, p. 6367 - 6371 (2011/10/02)

Fluorescent unnatural amino acids (UAAs), when genetically incorporated into proteins, can provide unique advantages for imaging biological processes in vivo. Synthesis of optically pure l-enantiomer of fluorescent UAAs is crucial for their effective application in live cells. An efficient six-step synthesis of l-3-(6-acetylnaphthalen-2-ylamino)-2-aminopropanoic acid (l-Anap), a genetically encodable and polarity-sensitive fluorescent UAA, has been developed. The synthesis takes advantage of a high-yield and enantiospecific Fukuyama-Mitsunobu reaction as the key transformation.

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