1590-25-6Relevant articles and documents
Girdler et al.
, p. 518 (1966)
Quantitative Design of Bright Fluorophores and AIEgens by the Accurate Prediction of Twisted Intramolecular Charge Transfer (TICT)
Chen, Jie,Chi, Weijie,Jiang, Xiao-Fang,Liu, Wenjuan,Liu, Xiaogang,Lyu, Da,McKechnie, Scott,Qiao, Qinglong,Tan, Davin,Wang, Chao,Xu, Ning,Xu, Zhaochao,Zhang, Qisheng,Zhou, Wei
, p. 10160 - 10172 (2020)
Inhibition of TICT can significantly increase the brightness of fluorescent materials. Accurate prediction of TICT is thus critical for the quantitative design of high-performance fluorophores and AIEgens. TICT of 14 types of popular organic fluorophores
NOVEL BENZIMIDAZOLE DERIVATIVES
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Paragraph 0252, (2020/01/22)
The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
N - heterocyclic compound, intermediate, preparation method, pharmaceutical composition and application (by machine translation)
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, (2017/10/31)
The invention discloses a N - heterocyclic compound, intermediate, preparation method, pharmaceutical composition and application. The invention of SHP2 N - heterocyclic compound to have high selectivity, can effectively inhibit the cell in the SHP2 downstream signal path ERK phosphorylation level, to tumor cells has very good inhibition activity, it has broad drug development prospects; its preparation method is simple, mild reaction conditions, high yield and purity, after treatment is simple, environmental protection, and is favorable for industrial production. (by machine translation)