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CYCLOPENTOLATE HYDROCHLORIDE

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CYCLOPENTOLATE HYDROCHLORIDE

EINECS 227-521-8
CAS No. 5870-29-1 Density g/cm3
PSA 49.77000 LogP 2.98210
Solubility N/A Melting Point 137-141°
Formula C17H25 N O3 . Cl H Boiling Point 409.7°Cat760mmHg
Molecular Weight 327.851 Flash Point 201.5°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: convulsions, distorted perceptions, hallucinations, toxic psychosis. When heated to decomposition it emits toxic fumes of NOx and HCl. See also ESTERS. Risk Codes N/A
Molecular Structure Molecular Structure of 5870-29-1 (CYCLOPENTOLATE HYDROCHLORIDE) Hazard Symbols N/A
Synonyms

Benzeneaceticacid, a-(1-hydroxycyclopentyl)-,2-(dimethylamino)ethyl ester, hydrochloride (9CI); Cyclopentaneacetic acid,1-hydroxy-a-phenyl-, 2-(dimethylamino)ethylester hydrochloride (8CI); (?à)-Cyclopentolate-hydrochloride; 2-(Dimethylamino)ethyl 1-hydroxy-a-phenylcyclopentaneacetatehydrochloride; Ak-Pentolate; Alnide; Cyclopentolate hydrochloride; Cyplegin;Mydplegic; Mydrilate; Zyklolat; b-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate hydrochloride

Article Data 1

CYCLOPENTOLATE HYDROCHLORIDE Chemical Properties

Product Name: Cyclopentolate hydrochloride (CAS NO.5870-29-1)


Molecular Formula: C17H26ClNO3
Molecular Weight: 327.85g/mol
Mol File: 5870-29-1.mol
Einecs: 227-521-8
Boiling point: 409.7 °C at 760 mmHg
Storage Temperature: −20°C
Flash Point: 201.5 °C
Enthalpy of Vaporization: 69.79 kJ/mol
Vapour Pressure: 1.91E-07 mmHg at 25°C
XLogP3-AA:
H-Bond Donor: 2
H-Bond Acceptor: 4

CYCLOPENTOLATE HYDROCHLORIDE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo ocular 50ug/kg/I (0.05mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: TOXIC PSYCHOSIS
American Journal of Ophthalmology. Vol. 105, Pg. 91, 1988.
child TDLo subcutaneous 40ug/kg (0.04mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Archives of Ophthalmology Vol. 87, Pg. 634, 1972.
mouse LD50 intraperitoneal 314mg/kg (314mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 106, Pg. 141, 1952.
mouse LD50 intravenous 63mg/kg (63mg/kg)   Drugs in Japan Vol. -, Pg. 516, 1995.
mouse LD50 oral 960mg/kg (960mg/kg)   Drugs in Japan Vol. 6, Pg. 314, 1982.
mouse LD50 subcutaneous 292mg/kg (292mg/kg)   Drugs in Japan Vol. -, Pg. 444, 1990.
rat LD50 oral > 4gm/kg (4000mg/kg)   Drugs in Japan Vol. 6, Pg. 314, 1982.
rat LD50 subcutaneous 2235mg/kg (2235mg/kg)   Drugs in Japan Vol. -, Pg. 444, 1990.

CYCLOPENTOLATE HYDROCHLORIDE Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects: convulsions, distorted perceptions, hallucinations, toxic psychosis. When heated to decomposition it emits toxic fumes of NOx and HCl. See also ESTERS.

CYCLOPENTOLATE HYDROCHLORIDE Specification

 Cyclopentolate hydrochloride ,its CAS NO. is 5870-29-1,the synonyms is Labotest-bb lt00244824 ; 2-Dimethylaminoethyl 1-hydroxy-alpha-phenylcyclopentaneacetate hydrochloride ; 2-(Dimethylamino)ethyl1-hydroxy-alpha-phenylcyclopentaneacetatehydrochlorid ; Alpha-(1-hydroxycyclopentyl)-benzeneaceticaci2-(dimethylamino)ethylest ; Beta-dimethylaminoethyl(1-hydroxycyclopentyl)phenylacetatehydrochloride ; Cyclogyl ; Cyclopentaneaceticacid,1-hydroxy-alpha-phenyl-,2-(dimethylamino)ethylester .

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