- Cefazedone
- Cefazedone sodium salt
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Cas Database |
| Name |
Cefazedone sodium salt |
EINECS | 264-293-9 |
| CAS No. | 63521-15-3 | Density | 1.78g/cm3 |
| PSA | 216.16000 | LogP | 0.84000 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C18H15 Cl2 N5 O5 S3 . Na | Boiling Point | N/A |
| Molecular Weight | 570.433 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. Used as an antibacterial agent. When heated to decomposition, it emits very toxic fumes of Cl−, NOx, Na2O, and SOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(3,5-dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7R)- (9CI); 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(3,5-dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-,monosodium salt, (6R-trans)-; Cefazedone sodium; Cefazedone sodium salt; EMD30087; NSC 304118; Refosporin |
Article Data | 8 |
Cefazedone sodium salt Chemical Properties
IUPAC Name: Sodium (6R,7R)-7-[[2-(3,5-dichloro-4-oxopyridin-1-yl)acetyl]amino]-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonyms: Sodium (6R-trans)-7-[[(3,5-dichloro-4-oxo-1(4H)-pyridyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;Cefazedone, sodium salt ; Sodium (6R,7R)-7-[[(3,5-dichloro-4-oxo-1(4H)-pyridyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ; (6R,7R)-7-[[2-(3,5-Dichloro-4-oxopyridin-1(4H)-yl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
Molecular Structure of Refosporen (CAS NO.63521-15-3) : 
Molecular Formula of Refosporen (CAS NO.63521-15-3) : C18H14Cl2N5NaO5S3
Molecular Weight of Refosporen (CAS NO.63521-15-3) : 570.42
CAS NO: 63521-15-3
EINECS: 264-293-9
Cefazedone sodium salt Uses
Refosporen (CAS NO.63521-15-3) has a significant effect of broad-spectrum antibacterial.
Cefazedone sodium salt Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 3gm/kg (3000mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. |
| mouse | LD50 | intramuscular | > 10gm/kg (10000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. | |
| mouse | LD50 | intravenous | 6800mg/kg (6800mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. |
| rabbit | LD50 | intravenous | 3200mg/kg (3200mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. |
| rat | LD50 | intramuscular | > 10gm/kg (10000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. | |
| rat | LD50 | intravenous | 4225mg/kg (4225mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 29, Pg. 424, 1979. |
Cefazedone sodium salt Safety Profile
Moderately toxic by intravenous route. An experimental teratogen. Experimental reproductive effects. Used as an antibacterial agent. When heated to decomposition, it emits very toxic fumes of Cl−, NOx, Na2O, and SOx.
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