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Cefditoren pivoxil

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Cefditoren pivoxil

EINECS 688-157-7
CAS No. 117467-28-4 Density 1.55 g/cm3
PSA 257.18000 LogP 3.20810
Solubility freely soluble in dilute hydrochloric acid and soluble at levels equal to 6.06 mg/mL in ethanol and <0.1 mg/mL in water. Melting Point 207-209 °C
Formula C25H28N6O7S3 Boiling Point N/A
Molecular Weight 620.731 Flash Point N/A
Transport Information N/A Appearance off-white powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 117467-28-4 (Cefditoren pivoxil) Hazard Symbols N/A
Synonyms

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[3(Z),6a,7b(Z)]]-;CCRIS 7768;Cefditorenpivaloyloxymethyl ester;Cefditoren pivoxyl;Cefditorin;ME1207;Meiact;Spectracef;

Article Data 15

Cefditoren pivoxil Chemical Properties

IUPAC Name: 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonyms of Cefditoren pivoxil (CAS NO.117467-28-4): Cefditoren Pivoxil [JAN] ; Cefditoren pivaloyloxymethyl ester ; ME 1207 ; CCRIS 7768 ; Cefditoren PI voxil ; Cefditorin ; ME 1207 ; Spectracef ; UNII-78THA212DH ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((1Z)-2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-,2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R-(3(Z),6-alpha,7-beta-(Z)))-
CAS NO: 117467-28-4
Classification Code: Anti-Bacterial Agents ; Anti-Infective Agents ; Drug / Therapeutic Agent ; Reproductive Effect
Molecular Formula of Cefditoren pivoxil (CAS NO.117467-28-4): C25H28N6O7S3
Molecular Weight: 620.7208
Molecular Structure:

Melting Point: 207-209°C
ProductCategories: Intermediates & Fine Chemicals ; Pharmaceuticals ; Sulfur & Selenium Compounds ; Cefditoren 
H bond acceptors: 13
H bond donors: 3
Freely Rotating Bonds: 12
Polar Surface Area: 225.61 Å2
Index of Refraction: 1.71
Molar Refractivity: 156.27 cm3
Molar Volume: 399.7 cm3
Surface Tension: 63.1 dyne/cm
Density of Cefditoren pivoxil (CAS NO.117467-28-4): 1.55 g/cm3

Cefditoren pivoxil Uses

 Cefditoren pivoxil (CAS NO.117467-28-4) is used for an antibacterial. It is the third generation cephalosporin.

Cefditoren pivoxil Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD oral > 2gm/kg (2000mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES Chemotherapy Vol. 40(Suppl,
mouse LD50 intraperitoneal 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Chemotherapy Vol. 40(Suppl,
mouse LD50 oral > 5100mg/kg (5100mg/kg)   Chemotherapy Vol. 40(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 oral > 5100mg/kg (5100mg/kg)   Chemotherapy Vol. 40(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Chemotherapy Vol. 40(Suppl,
rat LDLo intraperitoneal 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Chemotherapy Vol. 40(Suppl,

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