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Cefradine

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Name

Cefradine

EINECS 254-137-8
CAS No. 38821-53-3 Density 1.47 g/cm3
PSA 138.03000 LogP 1.37770
Solubility Soluble in water Melting Point 140-142 °C
Formula C16H19N3O4S Boiling Point 693.1 °C at 760 mmHg
Molecular Weight 349.411 Flash Point 373 °C
Transport Information N/A Appearance Solid
Safety 26-36 Risk Codes 36/37/38-42/43-20/21/22
Molecular Structure Molecular Structure of 38821-53-3 (Cefradine) Hazard Symbols HarmfulXn, IrritantXi
Synonyms

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[(amino-1,4-cyclohexadien-1-ylacetyl)amino]-3-methyl-8-oxo-, [6R-[6a,7b(R*)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2R)-amino-1,4-cyclohexadien-1-ylacetyl]amino]-3-methyl-8-oxo-, (6R,7R)-(9CI);7-[D-a-Amino-(1,4-cyclohexadienyl)acetamide]-3-desacetoxycephalosphoranicacid;Anspor;Cefradex;Cefradin;Cefradine;Cefrag;Cefro;Celex;Cephradin;Cephradine;Cesporan;Dimacef;Easkacef;Ecosporina;Eskacef;Lenzacef;Lisacef;Megacef;SQ 11436;Samedrin;Sefril;Velocef;Velosef;

Article Data 12

Cefradine Chemical Properties

Product Name: (6R-(6alpha,7))-((Amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Synonyms: (6r-(6alpha,7))-((amino-1,4-cyclohexadien-1-ylacetyl)amino)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;CEPHRADINE;CEPHRADINE HYDRATE;CEFRADIN;CEFRADINE;(6r-(6-alpha,7-beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-oxo;(6r-6alpha,7beta(r*)))-ien-1-ylacetyl)amino)-3-methyl-8-ox;5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((amino-1,4-cyclohexad 
Product Categories: Drug bulk
The Molecular formula of Sefril (CAS NO.38821-53-3): C16H21N3O5S
The Molecular Weight of Sefril (CAS NO.38821-53-3): 367.42 g/mol
Molecular Structure of Sefril (CAS NO.38821-53-3):   
EINECS: 254-137-8
Melting point: 140-142 deg C
storage temp.: Store at 0-5°C
Appearance: Solid
Density: 1.47 g/cm3
Flash Point: 373 °C
 Index of Refraction: 1.683
Surface Tension: 74.6 dyne/cm
Enthalpy of Vaporization: 110.65 kJ/mol
Boiling Point: 693.1 °C at 760 mmHg
Vapour Pressure of Sefril (CAS NO.38821-53-3): 4.85E-21 mmHg at 25 °C
 

Cefradine Toxicity Data With Reference

1.    

orl-wmn TDLo:5 mg/kg:SKN

    CUTIBC    CUTIS; Cutaneous Medicine for the Practitioner. 38 (1986),58.
2.    

orl-mus LD50:3549 mg/kg

    NKRZAZ    Chemotherapy (Tokyo). 23 (1975),37.
3.    

ipr-mus LD50:597 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
4.    

scu-mus LD50:2890 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.
5.    

ivn-mus LD50:3539 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),680.

Cefradine Safety Profile

Moderately toxic by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects: dermatitis. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.
The Hazard Codes of Sefril (CAS NO.38821-53-3):IrritantXi,HarmfulXn
The Risk Statements information of SEFRIL(38821-53-3): 20/21/22-36/37/38-42/43
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R42/43:May cause sensitization by inhalation and skin contact.
The Safety Statements information of Sefril (CAS NO.38821-53-3): 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing. 
RTECS XI0336000

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