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Name	Cetyl palmitate	EINECS	208-736-6
CAS No.	540-10-3	Density	0.858 g/cm³
PSA	26.30000	LogP	11.49220
Solubility	N/A	Melting Point	55-56 °C(lit.)
Formula	C₃₂H₆₄O₂	Boiling Point	507 °C at 760 mmHg
Molecular Weight	480.859	Flash Point	269.8 °C
Transport Information	N/A	Appearance	white to almost white crystalline powder
Safety	24/25	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Palmiticacid, cetyl ester (4CI);Palmitic acid, hexadecyl ester (6CI,7CI,8CI);1-Hexadecanol, palmitate (8CI);Cetin;Cetyl palmitate;Cutina CP;Cutina CPA;Estol 3694;Hexadecyl hexadecanoate;Hexadecyl palmitate;Kessco 653;N-SP;Nikkol N-SP;Nikkol N-SPV;Palmitic acid palmityl ester;Palmityl palmitate;Precifac;Precifac ATO;Radia 7500;S 653;Standamul 1616;Starfol Wax CG;Stepan 653;Stepantex 653;n-Hexadecyl hexadecanoate;n-Hexadecyln-hexadecanoate;	Article Data	39

Cetyl palmitate Synthetic route

: 36653-82-4
1-Hexadecanol

: 57-10-3
1-hexadecylcarboxylic acid

: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With zirconium(IV) oxychloride In 1,3,5-trimethyl-benzene at 162℃; for 24h;	99.5%
hafnium(IV) oxychloride In 1,3,5-trimethyl-benzene at 162℃; for 24h;	98.7%
With choline chloride; zinc(II) chloride at 110℃; for 10h;	97%

: 36653-82-4
1-Hexadecanol

: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With sodium bromate; sulfuric acid; sodium bromide In water at 20℃; for 24h;	99%
With [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); (2-((2-(diphenylphosphanyl)ethyl)(quinolin-2-ylmethyl)amino)ethyl)diphenylphosphine oxide; potassium tert-butylate In n-heptane at 100℃; for 16h;	86%

: 57-10-3
1-hexadecylcarboxylic acid

A: 36653-82-4
1-Hexadecanol

B: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With trimethylamine borane In xylene for 9h; Heating;	A 22% B 61%
With hydrogen; zirconium(IV) oxide In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;

: 57-10-3
1-hexadecylcarboxylic acid

: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In neat (no solvent) at 20 - 200℃; under 6000.6 Torr; for 24h; Autoclave; High pressure;	55%
With copper chromite; hydrogen at 360℃;

: 544-77-4
1-iodohexadecane

: 3508-01-8
silver palmitate

: 540-10-3
cetyl palmitate

: 36653-82-4
1-Hexadecanol

: 112-67-4
n-hexadecanoyl chloride

: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With quinoline; chloroform anfangs unter Kuehlung, dann bei Zimmertemperatur;
With diethyl ether; magnesium
With pyridine
In pyridine; chloroform

: 112-67-4
n-hexadecanoyl chloride

catyl alcohol: catyl alcohol

: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
at 180℃;

: 36653-82-4
1-Hexadecanol

: 544-63-8
n-tetradecanoic acid

: 57-10-3
1-hexadecylcarboxylic acid

A: 2599-01-1
tetradecanoic acid hexadecyl ester

B: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With phosphoric acid In hexane; water for 8.5h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In n-heptane; water for 18h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In water; toluene at 92℃; for 38.5h; Product distribution / selectivity; Heating / reflux;
With phosphoric acid In water; xylene at 105℃; for 1h; Product distribution / selectivity;
With phosphoric acid In water at 95℃; for 0.5h; Product distribution / selectivity;

: 57-10-3
1-hexadecylcarboxylic acid

A: 629-62-9
pentadecane

B: 544-76-3
Hexadecane

C: 36653-82-4
1-Hexadecanol

D: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;

: 57-10-3
1-hexadecylcarboxylic acid

A: 629-62-9
pentadecane

B: 36653-82-4
1-Hexadecanol

C: 540-10-3
cetyl palmitate

Conditions

Conditions	Yield
With hydrogen In dodecane at 20 - 260℃; under 9000.9 Torr; Kinetics; Autoclave;
With hydrogen In dodecane at 280℃; under 39003.9 Torr; for 6h; Catalytic behavior; Kinetics; Time;

Cetyl palmitate Chemical Properties

Chemical Name: Cetyl palmitate
IUPAC NAME: Hexadecyl hexadecanoate
CAS No.: 540-10-3
EINECS: 208-736-6
RTECS: RT4750000
Molecular Formula: C₃₂H₆₄O₂
Molecular Weight: 480.85 g/mol
Melting Point: 55-56 °C(lit.)
Density: 0.858 g/cm³
Flash Point: 269.8 °C
Boiling Point: 507 °C at 760 mmHg
Storage temp.: 2-8°C
Following is the structure of Hexadecyl palmitate (540-10-3):

The chemical synonymous of Hexadecyl palmitate (540-10-3) are Spermaceti ; Palmatic acid N-hexadecyl ester ; Palmitic acid palmityl ester ; Palmitic acid hexadecyl ester ; Palmitic acid cetyl ester ; Palmityl palmitate ; N-Hexadecylpalmitat

Cetyl palmitate Toxicity Data With Reference

skn-rbt 500 mg/24H MLD

JACTDZ Journal of the American College of Toxicology. 1 (2)(1982),13.

Cetyl palmitate Consensus Reports

Reported in EPA TSCA Inventory.

Cetyl palmitate Safety Profile

A skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety Statements about Hexadecyl palmitate (540-10-3):
S24/25 Avoid contact with skin and eyes.
Attention:
1. Storage: Store in a cool, dry place. Store in a tightly closed container.
2. Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

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