P450 (e.g. CYP17) inhibitor
P450 inhibitors, such as CYP17 inhibitors, are compounds that block the activity of cytochrome P450 enzymes, which play a crucial role in the metabolism of drugs, toxins, and endogenous substances like hormones. Specifically, CYP17 inhibitors target the enzyme CYP17A1 (17α-hydroxylase/17,20-lyase), which is involved in the production of androgens and other steroids. By inhibiting CYP17A1, these compounds can reduce androgen levels, making them particularly useful in the treatment of conditions like prostate cancer, where androgen-driven growth is a factor.
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