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Chrysin

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Name

Chrysin

EINECS 207-549-7
CAS No. 480-40-0 Density 1.443 g/cm3
PSA 70.67000 LogP 2.87120
Solubility N/A Melting Point 284-286 °C(lit.)
Formula C15H10O4 Boiling Point 491.9 °C at 760 mmHg
Molecular Weight 254.242 Flash Point 192.5 °C
Transport Information N/A Appearance beige powder
Safety 22-24/25-36-26 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 480-40-0 (Chrysin) Hazard Symbols IrritantXi
Synonyms

5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one;Flavone, 5,7-dihydroxy-;5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl- (9CI);NSC 407436;BRN 0233276;5-18-04-00076 (Beilstein Handbook Reference);5,7-Dihydroxyflavone;

Article Data 67

Chrysin Chemical Properties

Molecular structure of Chrysin (CAS NO.480-40-0) is:

Product Name: Chrysin
CAS Registry Number: 480-40-0
IUPAC Name: 5,7-dihydroxy-2-phenylchromen-4-one
Molecular Weight: 254.2375 [g/mol]
Molecular Formula: C15H10O4
XLogP3: 2.1
H-Bond Donor: 2
H-Bond Acceptor: 4 
EINECS: 207-549-7
Melting Point: 284-286 °C(lit.)
Surface Tension: 68.2 dyne/cm
Density: 1.443 g/cm3
Flash Point: 192.5 °C
Enthalpy of Vaporization: 78.76 kJ/mol
Boiling Point: 491.9 °C at 760 mmHg
Vapour Pressure: 2.67E-10 mmHg at 25°C
Storage temp.: 0-6°C
Stability: Stable. Incompatible with strong oxidizing agents.
Product Categories: Intermediates; FinE Chemical & Intermediates; Di-substituted Flavones; Biochemistry; Flavonoids

Chrysin Uses

 Chrysin (CAS NO.480-40-0) has been shown to induce an anti-inflammatory effect, most likely by inhibition of COX-2 expression and via IL-6 signaling. In herbal medicine, it is recommended as a remedy for anxiety, but there are no controlled data in humans available.

Chrysin Toxicity Data With Reference

1.    

dni-hmn-fbr 100 mg/L

    BCPCA6    Biochemical Pharmacology. 33 (1984),3823.

Chrysin Safety Profile

Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors. 
Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S36:Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: LK8329050
F: 10

Chrysin Specification

 Chrysin , its cas register number is 480-40-0. It also can be called 5,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one ; 5,7-Dihydroxyflavone ; 5-18-04-00076 (Beilstein Handbook Reference) ; BRN 0233276 ; Galangin flavanone ; NSC 407436 ; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-phenyl- (9CI) ; 5,7-Dihydroxy-2-phenyl-4H-benzo(b)pyran-4-one ; Flavone, 5,7-dihydroxy- .It is a beige powder. It was once believed to be an effective aromatase inhibitor, decreasing the levels of estrogen in the body. However, there is growing consensus that chrysin has no effect on estrogen levels in either animals or humans.

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