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| CAS No.: | 156-57-0 |
|---|---|
| Name: | Cysteamine hydrochloride |
| Molecular Structure: | |
|
|
|
| Formula: | C2H7NS.HCl |
| Molecular Weight: | 113.611 |
| Synonyms: | Ethanethiol,2-amino-, hydrochloride (8CI,9CI);2-Aminoethanthiol hydrochloride;2-Mercaptoethylamine hydrochloride;2-Thioethylamine hydrochloride;CI 9148;CT2000;Coated Cysteamine hydrochloride 25%; |
| EINECS: | 205-858-1 |
| Density: | 0.75 g/cm3 |
| Melting Point: | 66-70 °C |
| Boiling Point: | 133.6 °C at 760 mmHg |
| Flash Point: | 34.6 °C |
| Solubility: | very soluble in water |
| Appearance: | white crystalline powder with a strong and disagreeable smell |
| Hazard Symbols: |
Xn
|
| Risk Codes: | 22-36/37/38 |
| Safety: | 26-36/37/39 |
| PSA: | 64.82000 |
| LogP: | 1.37720 |

| Conditions | Yield |
|---|---|
| With hydrogenchloride; water under 2250.23 Torr; for 7h; Reflux; | 95.6% |

| Conditions | Yield |
|---|---|
| Stage #1: 2-chloroethanamine hydrochloride With sodium thiocarbonate In water at 40 - 60℃; Stage #2: With hydrogenchloride In water at 70 - 85℃; | 95% |

| Conditions | Yield |
|---|---|
| Stage #1: sodium 2‐aminoethyl sulfate With sodium thiocarbonate In water at 40 - 60℃; Stage #2: With hydrogenchloride In water at 70 - 85℃; | 93.5% |

| Conditions | Yield |
|---|---|
| Stage #1: sodium thiocarbonate; 2-chloroethanamine hydrochloride at 40 - 60℃; for 2.5h; Large scale; Stage #2: With hydrogenchloride In water at 70 - 80℃; for 2h; Large scale; | 93.27% |

| Conditions | Yield |
|---|---|
| Stage #1: sodium thiocarbonate; sodium 2‐aminoethyl sulfate at 40 - 60℃; for 2.5h; Large scale; Stage #2: With hydrogenchloride In water at 70 - 85℃; for 2h; Large scale; | 93.03% |

| Conditions | Yield |
|---|---|
| With potassium bromide; sodium nitrite In sulfuric acid; water | 61.4% |

| Conditions | Yield |
|---|---|
| With hydrogenchloride |

thiazolidine-2-thione


2-mercaptoethylamine hydrochloride

| Conditions | Yield |
|---|---|
| With hydrogenchloride for 168h; Heating; |

hydrochloride salt of (1-chloro-2-acetylamino-2-methyl-1-phenylpropyl) 2-aminoethyl sulfide

A

N-(2-methyl-1-oxo-1-phenylpropan-2-yl)acetamide

B

2-mercaptoethylamine hydrochloride

| Conditions | Yield |
|---|---|
| With water |


2-mercaptoethylamine hydrochloride

| Conditions | Yield |
|---|---|
| With hydrogenchloride at 155℃; |
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IUPAC Name :2-AMINOETHANETHIOL hydrochloride
Chemical Formula :C2H8ClNS
Cysteamine HCl is the manufacturing cimetidine as such drug intermediates.
Risk terms : R22 : Harmful if swallowed