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Cysteamine hydrochloride

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Name

Cysteamine hydrochloride

EINECS 205-858-1
CAS No. 156-57-0 Density 0.75 g/cm3
PSA 64.82000 LogP 1.37720
Solubility very soluble in water Melting Point 66-70 °C
Formula C2H7NS.HCl Boiling Point 133.6 °C at 760 mmHg
Molecular Weight 113.611 Flash Point 34.6 °C
Transport Information N/A Appearance white crystalline powder with a strong and disagreeable smell
Safety 26-36/37/39 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 156-57-0 (Cysteamine hydrochloride) Hazard Symbols HarmfulXn
Synonyms

Ethanethiol,2-amino-, hydrochloride (8CI,9CI);2-Aminoethanthiol hydrochloride;2-Mercaptoethylamine hydrochloride;2-Thioethylamine hydrochloride;CI 9148;CT2000;Coated Cysteamine hydrochloride 25%;

Article Data 16

Cysteamine hydrochloride Synthetic route

96-53-7

2-mercaptothiazoline

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water under 2250.23 Torr; for 7h; Reflux;95.6%
870-24-6

2-chloroethanamine hydrochloride

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
Stage #1: 2-chloroethanamine hydrochloride With sodium thiocarbonate In water at 40 - 60℃;
Stage #2: With hydrogenchloride In water at 70 - 85℃;
95%
666-03-5

sodium 2‐aminoethyl sulfate

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
Stage #1: sodium 2‐aminoethyl sulfate With sodium thiocarbonate In water at 40 - 60℃;
Stage #2: With hydrogenchloride In water at 70 - 85℃;
93.5%

sodium thiocarbonate

870-24-6

2-chloroethanamine hydrochloride

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
Stage #1: sodium thiocarbonate; 2-chloroethanamine hydrochloride at 40 - 60℃; for 2.5h; Large scale;
Stage #2: With hydrogenchloride In water at 70 - 80℃; for 2h; Large scale;
93.27%

sodium thiocarbonate

666-03-5

sodium 2‐aminoethyl sulfate

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
Stage #1: sodium thiocarbonate; sodium 2‐aminoethyl sulfate at 40 - 60℃; for 2.5h; Large scale;
Stage #2: With hydrogenchloride In water at 70 - 85℃; for 2h; Large scale;
93.03%
56-41-7

L-alanin

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With potassium bromide; sodium nitrite In sulfuric acid; water61.4%
4490-75-9

N-(2-mercaptoethyl)-phthalimide

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride
134469-06-0

thiazolidine-2-thione

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride for 168h; Heating;
107182-38-7

hydrochloride salt of (1-chloro-2-acetylamino-2-methyl-1-phenylpropyl) 2-aminoethyl sulfide

A

17582-78-4

N-(2-methyl-1-oxo-1-phenylpropan-2-yl)acetamide

B

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With water
μ-mercapto-thiazoline

μ-mercapto-thiazoline

156-57-0

2-mercaptoethylamine hydrochloride

Conditions
ConditionsYield
With hydrogenchloride at 155℃;

Cysteamine hydrochloride Chemical Properties

IUPAC Name :2-AMINOETHANETHIOL hydrochloride
Chemical Formula :C2H8ClNS

Cysteamine hydrochloride Uses

Cysteamine HCl is the manufacturing cimetidine as  such drug intermediates.

Cysteamine hydrochloride Toxicity Data With Reference

Risk terms : R22 : Harmful if swallowed

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