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DENOPAMINE

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Name

DENOPAMINE

EINECS N/A
CAS No. 71771-90-9 Density 1.177g/cm3
PSA 70.95000 LogP 2.66600
Solubility DMSO: 26 mg/mL, soluble Melting Point 135°C
Formula C18H23 N O4 Boiling Point 518.8°C at 760 mmHg
Molecular Weight 317.385 Flash Point 267.6°C
Transport Information N/A Appearance N/A
Safety Moderately toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. Risk Codes 62-63
Molecular Structure Molecular Structure of 71771-90-9 (R(-)-DENOPAMINE) Hazard Symbols HarmfulXn
Synonyms

Benzenemethanol,a-[[[2-(3,4-dimethoxyphenyl)ethyl]amino]methyl]-4-hydroxy-,(R)-; (-)-Denopamine; (R)-(-)-Denopamine; Carguto; Denopamine; Kalgut; TA 064

Article Data 12

DENOPAMINE Chemical Properties

Formula C18H23NO4 
Mol. mass 317.37 g/mol
form:  powder
color:  white
storage temp.:  2-8°C
solubility  DMSO: 26 mg/mL, soluble

DENOPAMINE Uses

Denopamine is a cardiotonic drug which can be used in the treatment of angina.
Denopamine may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary oedema.

DENOPAMINE Toxicity Data With Reference

1.   

orl-rat LD50:9369 mg/kg

   OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),751.
2.   

ipr-rat LD50:1785 mg/kg

   OYYAA2    Oyo Yakuri. Pharmacometrics. 32 (1986),751.

DENOPAMINE Safety Profile

Moderately toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
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