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Cas Database |
| Name |
DL-Norvaline |
EINECS | 212-082-7 |
| CAS No. | 760-78-1 | Density | 1.067 g/cm3 |
| PSA | 63.32000 | LogP | 0.89870 |
| Solubility | water: 1 g/10 mL (18 °C) | Melting Point |
≥300 °C (dec.) |
| Formula | C5H11NO2 | Boiling Point | 222.9 °C at 760 mmHg |
| Molecular Weight | 117.148 | Flash Point | 88.6 °C |
| Transport Information | N/A | Appearance | white to off-white crystals or crystalline powder |
| Safety | 22-24/25-37/39-26 | Risk Codes | 20/21/22-36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
DL-alpha-Aminovaleric acid;(+-)-Norvaline;DL-2-Aminopentanoic acid;2-Aminovaleric acid;(2R)-2-azaniumylpentanoate;DL-.alpha.-Aminovaleric acid;Valeric acid, 2-amino-, DL-;Norvaline, DL-;.alpha.-DL-Aminopentanoic acid;(2S)-2-azaniumylpentanoate;DL-Norvaline 99% min。;alpha-DL-Aminopentanoic acid; |
Article Data | 48 |
DL-Norvaline Synthetic route
- 56548-09-5
2-acetylamino-2-cyano-valeric acid ethyl ester
- 623-11-0
1-methyl-4-nitrosobenzene
- 760-78-1
2-aminopentanoic acid
- 56548-09-5
2-acetylamino-2-cyano-valeric acid ethyl ester
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogen bromide | |
| With hydrogenchloride |
| Conditions | Yield |
|---|---|
| With hydrogenchloride |
- 21486-54-4
2-hydroxyiminopentanoic acid
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride; palladium on activated charcoal under 7355.08 Torr; Hydrogenation; |
| Conditions | Yield |
|---|---|
| With hydrazine hydrate Umsetzung des erhaltenen Hydrazids mit NaNO2 in wss.HCl, Erwaermen des gebildeten Azids mit Aethanol und Aether und Kochen des Reaktionsprodukts mit konz.wss.HCl; |
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride; sodium nitrite Kochen des entstandenen Azids in Tetrachlorkohlenstoff und Erhitzen des Reaktionsprodukts mit konz.wss.HCl auf 120grad; | |
| Ueberfuehrung durch Propylmalonsaeure-monoazid; |
- 82518-89-6
acetylamino-propyl-malonic acid diethyl ester
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride | |
| With hydrogen bromide |
- 64527-14-6
2-phenylhydrazono-valeric acid
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride; zinc |
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With hydrogenchloride; zinc |
- 760-78-1
2-aminopentanoic acid
| Conditions | Yield |
|---|---|
| With water |
DL-Norvaline Chemical Properties
IUPAC Name: 2-Aminopentanoic acid
Empirical Formula: C5H11NO2
Molecular Weight: 117.1463 g/mol
Index of Refraction: 1.463
Density: 1.067 g/cm3
Flash Point: 88.6 °C
Melting point: 300 °C
Storage tempreture: Store at RT.
Water solubility: 1 g/10 mL (18 °C)
Solubility: Soluble in water
Boiling Point: 222.9 °C at 760 mmHg
Vapour Pressure: 0.0366 mmHg at 25 °C
Appearance: White to off-white crystals or crystalline powder
Structure of DL-Norvaline (CAS NO.760-78-1):
Product Category of DL-Norvaline (CAS NO.760-78-1): Norvaline;Peptide
DL-Norvaline Uses
DL-Norvaline (CAS NO.760-78-1) can be used as a pharmaceutical intermediate.
DL-Norvaline Toxicity Data With Reference
DL-Norvaline (CAS NO.760-78-1) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated.
DL-Norvaline Safety Profile
Hazard Codes: 
Xn
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
DL-Norvaline Specification
DL-Norvaline ,its cas register number is 760-78-1. It also can be called DL-2-Aminovaleric acid ; (+/-)-2-Aminopentanoic acid ; and DL-2-Aminovaleric acid . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water, and get medical aid immediately. Notes to physician: Treat supportively and symptomatically.
In addition, DL-Norvaline (CAS NO.760-78-1) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: nitrogen oxides, carbon monoxide, carbon dioxide.
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