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DL-Norvaline
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  • Name DL-Norvaline
  • EINECS212-082-7
  • CAS No. 760-78-1
  • Density1.067 g/cm3
  • PSA63.32000
  • LogP0.89870
  • Solubilitywater: 1 g/10 mL (18 °C)
  • Melting Point≥300 °C (dec.)
  • FormulaC5H11NO2
  • Boiling Point222.9 °C at 760 mmHg
  • Molecular Weight117.148
  • Flash Point88.6 °C
  • Transport InformationN/A
  • Appearancewhite to off-white crystals or crystalline powder
  • Safety22-24/25-37/39-26
  • Risk Codes20/21/22-36/37/38
  • Molecular Structure
    Molecular Structure of 760-78-1 (DL-Norvaline)
  • Hazard SymbolsHarmfulXn
  • SynonymsHarmfulXn
  • Article Data48

DL-Norvaline Synthetic route

56548-09-5

2-acetylamino-2-cyano-valeric acid ethyl ester

623-11-0

1-methyl-4-nitrosobenzene

760-78-1

2-aminopentanoic acid

56548-09-5

2-acetylamino-2-cyano-valeric acid ethyl ester

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogen bromide
With hydrogenchloride
74-90-8

hydrogen cyanide

40898-95-1

1-(-)-2-amino-1-butanol

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride
21486-54-4

2-hydroxyiminopentanoic acid

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride; palladium on activated charcoal under 7355.08 Torr; Hydrogenation;
6967-47-1

ethyl 2-cyanopentanoate

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrazine hydrate Umsetzung des erhaltenen Hydrazids mit NaNO2 in wss.HCl, Erwaermen des gebildeten Azids mit Aethanol und Aether und Kochen des Reaktionsprodukts mit konz.wss.HCl;

propyl-malonic acid monohydrazide

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite Kochen des entstandenen Azids in Tetrachlorkohlenstoff und Erhitzen des Reaktionsprodukts mit konz.wss.HCl auf 120grad;
Ueberfuehrung durch Propylmalonsaeure-monoazid;
82518-89-6

acetylamino-propyl-malonic acid diethyl ester

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride
With hydrogen bromide
64527-14-6

2-phenylhydrazono-valeric acid

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride; zinc

2-p-tolylhydrazono-valeric acid

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With hydrogenchloride; zinc

2-{[1-[5-((R)-2-Acetylamino-2-carboxy-ethylsulfanylmethyl)-3-hydroxy-2-methyl-pyridin-4-yl]-meth-(E)-ylidene]-amino}-pentanoic acid

760-78-1

2-aminopentanoic acid

Conditions
ConditionsYield
With water

DL-Norvaline Chemical Properties

IUPAC Name: 2-Aminopentanoic acid
Empirical Formula: C5H11NO2
Molecular Weight: 117.1463 g/mol
Index of Refraction: 1.463
Density: 1.067 g/cm3
Flash Point: 88.6 °C
Melting point: 300 °C
Storage tempreture: Store at RT.
Water solubility: 1 g/10 mL (18 °C)
Solubility: Soluble in water
Boiling Point: 222.9 °C at 760 mmHg
Vapour Pressure: 0.0366 mmHg at 25 °C
Appearance: White to off-white crystals or crystalline powder
Structure of DL-Norvaline (CAS NO.760-78-1):
                       
Product Category of DL-Norvaline (CAS NO.760-78-1): Norvaline;Peptide

DL-Norvaline Uses

 DL-Norvaline (CAS NO.760-78-1) can be used as a pharmaceutical intermediate.

DL-Norvaline Toxicity Data With Reference

 DL-Norvaline (CAS NO.760-78-1) hasn't been listed as a carcinogen by NTP, IARC, ACGIH, or CA Prop 65. And the toxicological properties have not been fully investigated.

DL-Norvaline Safety Profile

Hazard Codes: HarmfulXn
Risk Statements: 20/21/22-36/37/38 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26 
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection.

DL-Norvaline Specification

 DL-Norvaline ,its cas register number is 760-78-1. It also can be called DL-2-Aminovaleric acid ; (+/-)-2-Aminopentanoic acid ; and DL-2-Aminovaleric acid . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. And as soon as to get medical aid. Then you have the ingesting of the product : Wash mouth out with water, and get medical aid immediately. Notes to physician: Treat supportively and symptomatically.
In addition, DL-Norvaline (CAS NO.760-78-1) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: nitrogen oxides, carbon monoxide, carbon dioxide.

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