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Deoxycorticosterone acetate
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Name

Deoxycorticosterone acetate

 EINECS 200-275-9
CAS No. 56-47-3 Density 1.14 g/cm3
PSA 60.44000 LogP 4.26670
Solubility insoluble in water Melting Point 157 °C
Formula C23H32O4 Boiling Point 504.1 °C at 760 mmHg
Molecular Weight 372.505 Flash Point 218 °C
Transport Information UN 2811 Appearance Off-white solid
Safety 22-24/25 Risk Codes N/A
Molecular Structure Molecular Structure of 56-47-3 (Deoxycorticosterone acetate) Hazard Symbols N/A
Synonyms

11-Deoxycorticosterone,acetate (8CI);Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate (7CI);11-Deoxycorticosterone 21-acetate;11-Desoxycorticosterone acetate;21-Acetoxy-3,20-diketopregn-4-ene;21-Acetoxypregn-4-en-3,20-dione;21-Acetoxypregn-4-ene-3,20-dione;21-Hydroxypregn-4-ene-3,20-dione 21-acetate;21-Hydroxypregn-4-ene-3,20-dione acetate;21-Hydroxyprogesterone 21-acetate;4-Pregnene-3,20-dione 21-acetate;4-Pregnene-3,20-dione-21-ol acetate;Arcort;Bio-Corten;Cortacet;Cortate;Cortenil;Cortesan;Cortexone acetate;Cortifar;Cortigen;Cortinaq;Cortiron;Cortivis;Cortixyl;DCA;DOC acetate;DOCA;Decorten;Decortin;Decosteron;Decosterone;Decostrate;Deoxycorticosterone21-acetate;Deoxycorticosterone acetate;Deoxycortone acetate;Descorterone;Descotone;Desoxycorticosterone acetate;Desoxycortone acetate;Dorcostrin;Doxo;Doxycamon;Krinocorts;NSC 9567;Ocriten;Ocritena;Percorten;Percotol;Primocort;Primocortan;Sincortex;Steraq;Syncort;Syncorta;Syncortyl;Unidocan;

Article Data 51

Deoxycorticosterone acetate Synthetic route

64-85-7

21-Hydroxyprogesterone

108-24-7

acetic anhydride

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With pyridine In benzene89%
With pyridine
With pyridine Ambient temperature;
With pyridine
1171-90-0

3,20-dioxo-pregna-1,4-dien-21-yl acetate

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With thallium(III) nitrate trihydrate In diethylene glycol dimethyl ether for 24h; Ambient temperature;25%
110-86-1

pyridine

934167-52-9

20ξ-hydroxy-3-oxo-pregnen-(4)-al-(21)

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
beim anschliessenden Behandeln mit Acetanhydrid;
463-51-4

Ketene

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With acetone
With acetone
56-23-5

tetrachloromethane

128-08-5

N-Bromosuccinimide

15086-91-6

24,24-diphenyl-chola-4,20(22)ξ,23-trien-3-one

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
Reaktion ueber mehrere Stufen;
566-78-9

21-acetoxypregnenolone

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With aluminum tri-tert-butoxide; acetone
With chloroform; bromine Behandeln des erhaltenen Dibromids mit CrO3 in Essigsaeure und Behandeln einer Loesung des Reaktionsprodukts mit wss. CrCl2-Loesung unter Kohlendioxyd;
With chloroform; bromine Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure;
With chloroform; bromine Erwaermen des Reaktionsprodukts mit Zink-Pulver und Natriumacetat in Aether und anschliessend mit Essigsaeure und Erhitzen des danach isolierten Reaktionsprodukts mit Essigsaeure;
26987-64-4

21-chloropregn-4-ene-3,20-dione

127-09-3

sodium acetate

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With acetic acid
115098-53-8

21-acetoxy-3β-formyloxy-pregn-5-en-20-one

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With cyclohexanone; aluminum isopropoxide
20576-46-9

11-deoxy-21-iodocorticosterone

127-08-2

potassium acetate

56-47-3

deoxycorticosterone acetate

15086-91-6

24,24-diphenyl-chola-4,20(22)ξ,23-trien-3-one

56-47-3

deoxycorticosterone acetate

Conditions
ConditionsYield
With tetrachloromethane; N-Bromosuccinimide unter Belichtung anschliessend des Reaktionsprodukts mit Kaliumacetat in Essigsaeure und Behandeln einer Loesung des danach isolierten Reaktionsprodukts in Essigsaeure und 1.2-Dichlor-aethan mit CrO3 in wss. Essigsaeure;

Deoxycorticosterone acetate Chemical Properties

Chemical Name: Deoxycorticosterone acetate
IUPAC NAME: [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS No.: 56-47-3
EINECS: 200-275-9
RTECS: HG0525000
RTECS Class: Tumorigen ;  Reproductive Effector
Molecular Formula: C23H32O4
Molecular Weight: 372.5 g/mol
Melting Point: 157°C
Density: 1.14 g/cm3 
Flash Point: 218 °C
Boiling Point: 504.1 °C at 760 mmHg
Following is the structure of 11-Deoxycorticosterone acetate (56-47-3):


Product Categories about 11-Deoxycorticosterone acetate (56-47-3) are Biochemistry ; Hydroxyketosteroids ; Steroids
The chemical synonymous of 11-Deoxycorticosterone acetate (56-47-3) are 11-Deoxycorticosterone21-acetate ; 20-Dione,21-hydroxy-pregn-4-ene-acetate ; 21-Acetoxy-3,20-diketopregn-4-ene ; 21-Acetyloxypregn-4-ene-3,20-dione ; 21-Hydroxypregn-4-ene-3,20-dione21-acetate ; 4-Pregnene-3,20-dione-21-olacetate ; Arcort ; Bio-Corten

Deoxycorticosterone acetate Uses

 11-Deoxycorticosterone acetate (56-47-3) is mainly used for biochemical studies and used as an adrenal cortex hormones drugs,it also has anti-inflammatory, anti-allergy effects.

Deoxycorticosterone acetate Safety Profile

Questionable carcinogen with experimental tumorigenic data. Experimental reproductive effects. A steroid. When heated to decomposition it emits acrid smoke and irritating fumes.
Safety Statements about 11-Deoxycorticosterone acetate (56-47-3):
S22 Do not breathe dust.
S24/25: Avoid contact with skin and eyes.

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