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Difluoromethyl 2,2,2-trifluoroethylether

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Name

Difluoromethyl 2,2,2-trifluoroethylether

EINECS N/A
CAS No. 1885-48-9 Density 1.338 g/cm3
PSA 9.23000 LogP 1.78790
Solubility N/A Melting Point -23.15°C
Formula C3H3F5O Boiling Point 13.3 °C at 760 mmHg
Molecular Weight 150.048 Flash Point 112.5°C
Transport Information N/A Appearance N/A
Safety 26-36/37/39 Risk Codes 10-36/37/38
Molecular Structure Molecular Structure of 1885-48-9 (DIFLUOROMETHYL 2,2,2-TRIFLUOROETHYL ETHER) Hazard Symbols IrritantXi
Synonyms

Ether,difluoromethyl 2,2,2-trifluoroethyl (7CI,8CI);2,2,2-Trifluoroethyldifluoromethyl ether;2-(Difluoromethoxy)-1,1,1-trifluoroethane;Difluoromethyl2,2,2-trifluoroethyl ether;HFC-E 245;HFE 245fa2;HFE 245mf;R-E 245fa1;

Article Data 2

Difluoromethyl 2,2,2-trifluoroethylether Specification

The Ethane,2-(difluoromethoxy)-1,1,1-trifluoro-, with the CAS registry number 1885-48-9, is also known as Ether,difluoromethyl 2,2,2-trifluoroethyl (7CI,8CI). It belongs to the product categories of Refrigerants. This chemical's molecular formula is C3H3F5O and molecular weight is 150.0473. What's more, both its IUPAC name and systematic name are the same which is called 2-(Difluoromethoxy)-1,1,1-trifluoroethane. 

Physical properties about Ethane,2-(difluoromethoxy)-1,1,1-trifluoro- are: (1)ACD/LogP: 1.35; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.35; (4)ACD/LogD (pH 7.4): 1.35; (5)ACD/BCF (pH 5.5): 6.22; (6)ACD/BCF (pH 7.4): 6.22; (7)ACD/KOC (pH 5.5): 128.7; (8)ACD/KOC (pH 7.4): 128.7; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 9.23 Å2; (13)Index of Refraction: 1.261; (14)Molar Refractivity: 18.43 cm3; (15)Molar Volume: 112 cm3; (16)Polarizability: 7.3×10-24 cm3; (17)Surface Tension: 12.6 dyne/cm; (18)Density: 1.338 g/cm3; (19)Enthalpy of Vaporization: 25.02 kJ/mol; (20)Boiling Point: 13.3 °C at 760 mmHg; (21)Vapour Pressure: 1150 mmHg at 25 °C.

Preparation of Ethane,2-(difluoromethoxy)-1,1,1-trifluoro-: this chemical is prepared by 2,2,2-Trifluoro-ethanol and Difluoro-fluorosulfonyl-acetic acid. This reaction needs reagent Na2SO4 and solvent acetonitrile at temperature of 45 °C. The reaction time is 2 hours. The yield is 38 %. And the reaction equation is as followed:

Ethane,2-(difluoromethoxy)-1,1,1-trifluoro- is prepared by 2,2,2-Trifluoro-ethanol and Difluoro-fluorosulfonyl-acetic acid

Use of Ethane,2-(difluoromethoxy)-1,1,1-trifluoro-: it is used to produce other chemicals. For example, it is used to produce 1,2-Dichloro-1,1,2,3-tetrafluoro-3-(2,2,2-trifluoro-ethoxy)-propane. The reaction occurs with reagent SbF5 at temperature of 10-25 °C. The yield is 43 %. And the reaction equation is as followed:

Ethane,2-(difluoromethoxy)-1,1,1-trifluoro- is used to produce 1,2-Dichloro-1,1,2,3-tetrafluoro-3-(2,2,2-trifluoro-ethoxy)-propane

When you are dealing with this chemical, you should be very careful. This chemical is flammable and it is irritating to eyes, respiratory system and skin. Therefore, you should wear suitable protective clothing, gloves and eye/face protection. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1) SMILES: FC(F)(F)COC(F)F
(2) InChI: InChI=1/C3H3F5O/c4-2(5)9-1-3(6,7)8/h2H,1H2
(3) InChIKey: ZASBKNPRLPFSCA-UHFFFAOYAZ

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