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Name	ETHAMBUTOL DIHYDROCHLORIDE	EINECS	213-970-7
CAS No.	1070-11-7	Density	N/A
PSA	64.52000	LogP	2.09320
Solubility	Slightly soluble in water	Melting Point	198-200 °C
Formula	C₁₀H₂₄N₂O₂^.2(HCl)	Boiling Point	345.3 °C at 760 mmHg
Molecular Weight	277.235	Flash Point	113.7 °C
Transport Information	N/A	Appearance	white powder
Safety	53-22-36/37/39-45-36/37-26	Risk Codes	61-36/37/38
Molecular Structure		Hazard Symbols	T,Xi
Synonyms	(+)-2,2-(Ethylenediimino)-di-1-butanol dihydrochloride;Prestwick_208;(2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol dihydrochloride;1-Butanol, 2,2-(1,2-ethanediyldiimino)bis-, dihydrochloride, (R-(R,R))- (9CI);Ethambutol hydrochloride;CL 40881;(S-(R,R))-2,2-(Ethylenediimino)dibutan-1-ol dihydrochloride;1-Butanol,2,2'-(1,2-ethanediyldiimino)bis-,dihydrochloride,(2S,2'S)-;Ethambutol hydrochloride (JP14/USP);Myambutol;1-Butanol, 2,2-(1,2-ethanediyldiimino)bis-, dihydrochloride, (S-(R,R))-;Ethambutol hydrochloride [USAN:JAN];(2R)-2-[2-[[(2R)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol dihydrochloride;Myambutol (TN);Ethambutol HCl;

ETHAMBUTOL DIHYDROCHLORIDE Chemical Properties

IUPAC Name: (2S)-2-[2-[[(2S)-1-hydroxybutan-2-yl]amino]ethylamino]butan-1-ol
dihydrochloride
The MF of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7): C₁₀H₂₄N₂O₂·2(HCl)
The MW of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7): 277.23
EINECS: 213-970-7
Density: 0.987 g/cm³
Flash Point: 113.7 °C
Boiling Point: 345.3 °C at 760 mmHg
Index of Refraction: 1.477
Synonyms: ETHAMBUTOL HCL; Ethambutol Hydrochloride; 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride; [S-(R*,R*)]-2,2'-(Ethylenediimino)dibutan-1-ol dihydrochloride
The Structure of ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7):

ETHAMBUTOL DIHYDROCHLORIDE Uses

ETHAMBUTOL DIHYDROCHLORIDE(1070-11-7) is used as antibacterial.

ETHAMBUTOL DIHYDROCHLORIDE Toxicity Data With Reference

1.	mnt-mus-orl 50 mg/kg	IRLCDZ IRCS Medical Science: Library Compendium. 10 (1982),135.
2.	spm-mus-orl 12,500 µg/kg	IRLCDZ IRCS Medical Science: Library Compendium. 10 (1982),135.
3.	orl-man TDLo:45 mg/kg/3D-I:EYE	BJDCAT British Journal of Diseases of the Chest. 80 (1986),288.
4.	orl-man TDLo:46 mg/kg/3D-I:EYE	PGMJAO Postgraduate Medical Journal. 61 (1985),811.
5.	unr-wmn TDLo:720 mg/kg/48D:EYE	ANOPB5 Annals of Ophthalmology. 2 (1970),578.
6.	orl-rat LD50:6800 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70.
7.	ipr-rat LD50:1200 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70.
8.	ivn-rat LD50:300 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70.
9.	orl-mus LD50:8900 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70.
10.	scu-mus LD50:1800 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 2 (1968),70.
11.	<p class="cardite

ETHAMBUTOL DIHYDROCHLORIDE Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by ingestion. Human systemic effects: constriction of the pupil, visual field changes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x and HCl. See also AMINES.
Hazard Codes:

T: Toxic;
Risk Statements: R61: May cause harm to the unborn child
Safety Statements:
S53: Avoid exposure - obtain special instruction before use
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

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