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EINECS 204-399-4
CAS No. 120-47-8 Density 1.168 g/cm3
PSA 46.53000 LogP 1.56890
Solubility Soluble in ethanol, ether and acetone, slightly soluble in water Melting Point 114-117 °C(lit.)
Formula C9H10O3 Boiling Point 297.5 °C at 760 mmHg
Molecular Weight 166.19 Flash Point 120.3 °C
Transport Information Appearance white crystalline powder
Safety 26-36-24/25 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 120-47-8 (Benzoic acid,4-hydroxy-, ethyl ester) Hazard Symbols IrritantXi

Benzoicacid, p-hydroxy-, ethyl ester (6CI,8CI);4-(Ethoxycarbonyl)phenol;4-Carbethoxyphenol;4-Hydroxybenzoic acid ethyl ester;Aseptin A;Aseptine A;Aseptoform E;Bonomold OE;E 214;Easeptol;Ethyl 4-hydroxybenzoate;EthylButex;Ethyl nipagin;Ethyl p-hydroxybenzoate;Ethyl parasept;Ethylparaben;Mekkings E;Mycocten;p-(Ethoxycarbonyl)phenol;p-Carbethoxyphenol;p-Hydroxybenzoate ethyl ester;


Ethylparaben Chemical Properties

Empirical Formula: C9H10O3
Molecular Weight: 166.1739 g/mol
EINECS: 204-399-4 
Index of Refraction: 1.538
Density: 1.168 g/cm3
Flash Point: 120.3 °C
Melting point: 115-118 °C(lit.)
Storage tempreture: 0-6 °C
Appearance: White crystalline powder
Enthalpy of Vaporization: 55.89 kJ/mol
Boiling Point: 297.5 °C at 760 mmHg
Vapour Pressure: 0.000759 mmHg at 25 °C
Solubility: Soluble in ethanol, ether and acetone, slightly soluble in water
Structure of Ethylparaben (CAS NO.120-47-8):
IUPAC Name: Ethyl 4-hydroxybenzoate
Product Category of Ethylparaben (CAS NO.120-47-8): Pharmaceutical Raw Materials;Aromatic Esters

Ethylparaben Uses

 Ethylparaben (CAS NO.120-47-8) is used as a food preservative, and is also used in the pharmaceutical, leather and other industries.

Ethylparaben Production

 Ethylparaben (CAS NO.120-47-8) can be obtained from the right-hydroxy benzoic acid and ethanol in the presence of sulfuric acid as catalyst for esterification, after that having them in water for crystallization, and then through filter and pickling to get the product.

Ethylparaben Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 5gm/kg (5000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 81, 1974.
guinea pig LD50 oral 2gm/kg (2000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 81, 1974.
mouse LD50 intraperitoneal 520mg/kg (520mg/kg)   Drug Standards. Vol. 20, Pg. 89, 1952.
mouse LD50 oral 3gm/kg (3000mg/kg)   Bromatologia i Chemia Toksykologiczna. Vol. 14, Pg. 301, 1981.
rabbit LD50 oral 5gm/kg (5000mg/kg)   FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 81, 1974.
rat LD oral > 200mg/kg (200mg/kg)   Acta Obstetrica et Gynaecologica Japonica, English Edition. Vol. 22, Pg. 94, 1975.

Ethylparaben Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-24/25 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

Ethylparaben Specification

 Ethylparaben , its cas register number is 120-47-8. It also can be called Ethyl paraben ; 4-(Ethoxycarbonyl)phenol ; Ethyl 4-hydroxybenzoate ; p-Hydroxybenzoate ethyl ester ; Ethyl butex ; 4-Hydroxybenzoic acid ethyl ester ; and Ethyl p-hydroxybenzoate . It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately. Notes to physician: Treat supportively and symptomatically.
In addition, Ethylparaben (CAS NO.120-47-8) is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide.

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