Novel 4-aminoquinolines through microwave-assisted SNAr reactions: A practical route to antimalarial agents

Article abstract of DOI:10.1002/ejoc.200700612

4-Aminoquinolines have recently been indicated to be an important class of chemotherapeutic agents for artemisinin-based antimalarial combination therapy. A rapid, cheap, possibly clean and scalable route to 4-aminoquinolines endowed with multiple diversi