
Journal of Medicinal Chemistry p. 748 - 751 (1986)
Update date:2022-08-04
Topics:
Burke, Terrence R.
Jacobson, Arthur E.
Rice, Kenner C.
Weissman, Ben Avi
Huang, Hsueh-Cheng
Silverton, J. V.
The synthesis of racemic (3α,6aα,11aβ)-1,3,4,5,6,11a-hexahydro-2-methyl-2H-3,6a-methanobenzofuro<2,3-c>azocin-10-ol (2d) is described.The route used acid-catalyzed ring closure of enamine 5 to yield the unsaturated phenylmorphan 6.Conversion of 6 to oxide
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