Probes for Narcotic Receptor Mediated Phenomena. 9. Synthesis of (+/-)-(3α,6aα,11aβ)-1,3,4,5,6,11a-Hexahydro-2-methyl-2H-3,6a-methanobenzofuroazocin-10-ol, an Oxide-Bridged 5-(m-Hydroxyphenyl)morphan

DOI: 10.1021/jm00155a026

Source and publish data:

Journal of Medicinal Chemistry p. 748 - 751 (1986)

Update date:2022-08-04

Topics:

Authors:

Burke, Terrence R.

Jacobson, Arthur E.

Rice, Kenner C.

Weissman, Ben Avi

Huang, Hsueh-Cheng

Silverton, J. V.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00155a026

The synthesis of racemic (3α,6aα,11aβ)-1,3,4,5,6,11a-hexahydro-2-methyl-2H-3,6a-methanobenzofuro<2,3-c>azocin-10-ol (2d) is described.The route used acid-catalyzed ring closure of enamine 5 to yield the unsaturated phenylmorphan 6.Conversion of 6 to oxide

Full text of DOI:10.1021/jm00155a026

Products guided by the article

Product name:(+/-)-2-methyl-4-bromo-5-(2,3-dihydroxyphenyl)-2-azabicyclo<3.3.1>nonane hydrobromide

Cas No:100448-08-6

R&D Labs maybe for 100448-08-6

HANGZHOU ICH BIOFARM CO.,LTD

Contact:+86-571-28186845

Address:Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
Allicon Pharmaceuticals,Inc.

Contact:+86-519-86339586，13584329896

Address:Changzhou Scientific and Education Park
Huixian Tiankai Paper Making Agent CO.,Ltd.

Contact:+86-373-6899808

Address:Mengdian Industrial Avenue,Huixian,Xinxiang,Henan,China
Wuxi Morality Chemical Co., Ltd(expird)

Contact:

Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:No.199, Ningbo Avenue, Fengxin industrial park, Fengxin county, Yichun city, Jiangxi

Relevant to this article

Doi:10.1021/ja01521a024
(1959)
Synthesis of diazatricyclic core of madangamines from cis- perhydroisoquinolines

Doi:10.1021/jo702340w
(2008)
Synthesis of 7-β-(N,N-dialkylamino)ethoxy derivatives of natural isoflavones and 4-aryl-3-[2-hydroxy-4-β-(N,N-dialkylamino) ethoxy]phenylpyrazoles based on them

Doi:10.1007/s10600-013-0500-9
(2013)
Chiral N-heterocyclic carbene-Pd(0)-catalyzed asymmetric diamination of conjugated dienes and triene

Doi:10.1021/jo702167u
(2008)
Combining semi-synthesis with plant and microbial biocatalysis: New frontiers in producing a chemical arsenal against cancer

Doi:10.1039/c8ra02184h
(2018)
Doi:10.1002/ardp.19582910505
(1958)

Article Doi