added and the mixture is stirred. Then 1 mL of acetone is added and 20 μL of the mixture is
added to 980 μL of acetonitrile. A second dilution with 20 μL of the previously prepared solution
is added to 980 μL of acetonitrile to give a sample from 0 (0% yield) to 60 μM (100% yield) of
either thiazole, which is then analyzed by LC/MS (measurement of UV absorption at 254 nm).
ASSOCIATED CONTENT
*Supporting Information: Experimental procedures and characterization of all new compounds
including NMR spectroscopy data.
Acknowledgments
We are grateful to Arnaud Mars for his contribution to this project, Dr. Marie-France Herent
and Prof. Giulio Muccioli (UCL, LDRI, BPBL) for helpful discussions and assistance with HRMS
and Nikolay Tumanov (PC2 platform, Unamur) for assistance with X-ray diffraction
experiments. This work was supported by the Université catholique de Louvain (UCL-FSR),
the National Fund for Scientific Research in Belgium (F.R.S.-FNRS) from which RF is an
honorary research associate, the Télévie, the Fonds Maisin, the Fonds Spéciaux de
Recherche (FSR), the Actions de Recherche Concertées (ARC) and the Fondatioun
Kriibskrank Kanner (Luxembourg). RF and ED shares the last authorship position.
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