Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A

Article abstract of DOI:10.1016/j.bmcl.2007.10.051

In-silico virtual screening of bacterial surface enzyme Staphylococcus aureus Sortase A against commercial compound libraries using FlexX software package has led to the identification of novel inhibitors. Inhibition of enzyme catalytic activity was deter