A synthetic route to potential inhibitors of 5-lipoxygenase, I

DOI: 10.1002/ardp.19863190610

Source and publish data:

Archiv der Pharmazie p. 530 - 537 (1986)

Update date:2022-08-04

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Authors:

Folkers Folkers

Roth Roth

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Article abstract of DOI:10.1002/ardp.19863190610

Derivatives of enamino(cyano)pyrrol are able to inhibit 5-lipoxygenase. Bulky substituents at position 2 of an aromatic moiety seem to increase the inhibitory potency. As a model compound, a 2,4-dinitrophenyl derivative was synthesized, and a new syntheti

Full text of DOI:10.1002/ardp.19863190610

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Product name:2-(2,4-Dinitrophenyl)amino-3-cyano-4,5-dimethylpyrrol

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