A synthetic route to potential inhibitors of 5-lipoxygenase, I

DOI: 10.1002/ardp.19863190610

Source and publish data:

Archiv der Pharmazie p. 530 - 537 (1986)

Update date:2022-08-04

Topics:

Authors:

Folkers Folkers

Roth Roth

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ardp.19863190610

Derivatives of enamino(cyano)pyrrol are able to inhibit 5-lipoxygenase. Bulky substituents at position 2 of an aromatic moiety seem to increase the inhibitory potency. As a model compound, a 2,4-dinitrophenyl derivative was synthesized, and a new syntheti

Full text of DOI:10.1002/ardp.19863190610

Products guided by the article

Product name:2-(2,4-Dinitrophenyl)amino-3-cyano-4,5-dimethylpyrrol

Cas No:101337-37-5

R&D Labs maybe for 101337-37-5

shijiazhuang shuanglian chemical industry co.,ltd

Contact:0311-82190302

Address:Luquan Intersection , Shijiazhuang--Taiyuan Expressway，Shijiazhuang City
ZHEJIANG JIANYE CHEMICAL CO.,LTD.

Contact:86-571-64149273,64149234

Address:No. 48, Fuxi Road, Meicheng Town
Nanjing Chemzam Pharmtech Co., Ltd.

Contact:+86-25-86462165,+86-13915979898

Address:C5-1，6 Maiyue Road，Maigaoqiao，Nanjing，Jiangsu，China
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
KangZhiYuan Pharmaceutical Company Limited

Contact:(Sabrina)86-20-85273232

Address:4th floor, building B, Dadi industry zone, Tangxia, Tianhe, Guangzhou, China

Relevant to this article

A one-pot, solid-phase synthesis of secondary amines from reactive alkyl halides and an alkyl azide

Doi:10.1055/s-2007-990927
(2008)
Novel one-pot, three-component synthesis of new 2-alkyl-5-aryl-(1H)- pyrrole-4-ol in water

Doi:10.1021/jo702385n
(2008)
An efficient, one-pot synthesis of fosfomycin dialkyl esters from (R)-2-tosyloxypropanal

Doi:10.3987/com-07-s(w)45
(2007)
Exploiting self-assembly for ligand-scaffold optimization: Substrate-tailored ligands for efficient catalytic asymmetric hydroboration

Doi:10.1002/anie.200703127
(2008)
A new 4-(N,N-dimethylamino)benzonitrile (DMABN) derivative with tetrathiafulvalene unit: modulation of the dual fluorescence of DMABN by redox reaction of tetrathiafulvalene unit

Doi:10.1016/j.tetlet.2007.12.087
(2008)
Doi:10.1016/S0020-1693(00)87900-1
(1987)

Article Doi