Synthesis of chiral pyridyl alcohols using a two-step catalytic approach

Article abstract of DOI:10.1055/s-2007-990903

Chira l pyridyl alcohols have been prepared by developing a two-step approach that uses the asymmetric cyanation of aldehydes to give cyanohydrins and subsequent [2+2+2]-cyclotrimerization reaction with acetylene. Georg Thieme Verlag Stuttgart.