Synthesis of 2-substituted 2H-chromenes using potassium vinyltrifluoroborates

Article abstract of DOI:10.1016/j.tetlet.2008.01.008

2H-Chromenes were synthesized from salicylaldehyde using potassium vinylic borates in the presence of secondary amines. We synthesized these 2H-chromene derivatives as a part of an ongoing project to develop inhibitors for TGF-β receptors. Potassium vinyl