Organic Synthesis with Enzymes. 3. TBADH-Catalyzed Reduction of Chloro Ketones. Total Synthesis of (+)-(S,S)-(cis-6-Methyltetrahydropyran-2-yl)acetic Acid: A Civet Constituent

DOI: 10.1021/ja00272a051

Source and publish data:

Journal of the American Chemical Society p. 3474 - 3480 (1986)

Update date:2022-08-05

Topics:

Authors:

Keinan, Ehud

Seth, Kamal K.

Lamed, Raphael

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00272a051

Highly enantioselective reduction of aliphatic chloro ketones catalyzed by Thermoanaerobium brockii alcohol dehydrogenase (TBADH) afforded the corresponding S chloro alcohols, which are new and useful chiral bifunctional building blocks.The synthetic pote

Full text of DOI:10.1021/ja00272a051

Products guided by the article

Product name:(7S)-(+)-3-hydroxy-1-phenyl-7-(tetrahydropyranyl-2-oxy)oct-1-ene

Cas No:102108-36-1

R&D Labs maybe for 102108-36-1

Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Jinan Baozhao Pharmaceutical Co., Ltd

Contact:0086-531-86397156 82371858 82371868

Address:Huaneng Road, Jinan, Shandong ,China
Nanjing Capatue Chemical Co., Ltd

Contact:+86-25-86371192 +86-025-85720158

Address:No.20 Jiangjun Avenue, Jiangning Economic & Technical Development Zone
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou

Relevant to this article

Synthesis of deuterium labeled (±)-2,5-dimethoxyamphetamine (DMA), (±)-4-bromo-2,5-dimethoxyamphetamine (DOB), and (±)-4- methoxyamphetamine (PMA) as internal standards for quantitative analyses by GC-MS

Doi:10.1002/jccs.200700070
(2007)
Discovery and SAR of novel and selective inhibitors of urokinase plasminogen activator (uPA) with an imidazo[1,2-A]pyridine scaffold

Doi:10.1021/acs.jmedchem.5b01171
(2015)
Rapid synthesis of 3-aminoimidazo[1,2-a]pyridines and pyrazines

Doi:10.1080/00397910701862931
(2008)
Enantioselective addition of ArTi(OⁱPr)₃ to aldehydes catalyzed by a titanium complex of an N-sulfonylated amino alcohol

Doi:10.1039/c4ra14173c
(2015)
A concise synthesis of chilenine via a sequential reaction process

Doi:10.1016/j.tetlet.2008.02.057
(2008)
Novel (thio)barbituric-phenoxy-N-phenylacetamide derivatives as potent urease inhibitors: synthesis, in vitro urease inhibition, and in silico evaluations

Doi:10.1007/s11224-020-01617-6
(2021)

Article Doi