Gold(I)-Catalyzed Asymmetric Aldol Reaction of N-Methoxy-N-methyl-α-isocyanoacetamide (α-Isocyano Weinreb Amide). An Efficient Synthesis of Optically Active β-Hydroxy α-Amino Aldehydes and Ketones

DOI: 10.1021/jo00111a034

Source and publish data:

Journal of Organic Chemistry p. 1727 - 1732 (1995)

Update date:2022-07-31

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Authors:

Sawamura, Masaya

Nakayama, Yuki

Kato, Tomoki

Ito, Yoshihiko

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Article abstract of DOI:10.1021/jo00111a034

Asymmetric aldol reaction of N-methoxy-N-methyl-α-isocyanoacetamide (α-isocyano Weinreb amide) with aldehydes in the presence of a gold(I) catalyst prepared in situ from BF4 and chiral fe

Full text of DOI:10.1021/jo00111a034

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