Gold(I)-Catalyzed Asymmetric Aldol Reaction of N-Methoxy-N-methyl-α-isocyanoacetamide (α-Isocyano Weinreb Amide). An Efficient Synthesis of Optically Active β-Hydroxy α-Amino Aldehydes and Ketones

DOI: 10.1021/jo00111a034

Source and publish data:

Journal of Organic Chemistry p. 1727 - 1732 (1995)

Update date:2022-07-31

Topics:

Authors:

Sawamura, Masaya

Nakayama, Yuki

Kato, Tomoki

Ito, Yoshihiko

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00111a034

Asymmetric aldol reaction of N-methoxy-N-methyl-α-isocyanoacetamide (α-isocyano Weinreb amide) with aldehydes in the presence of a gold(I) catalyst prepared in situ from BF4 and chiral fe

Full text of DOI:10.1021/jo00111a034

Products guided by the article

Product name:(E)-(2S,3R)-2-Amino-6-benzyloxy-3-hydroxy-hex-4-enoic acid methoxy-methyl-amide

Cas No:1026840-32-3

R&D Labs maybe for 1026840-32-3

Shanghai Hohance Chemical Co., ltd

Contact:13914753421

Address:Fl.5；Bld. 70, Lane 1500; Xinfei Road
Shandong Yaroma Perfumery Co., Ltd.

Contact:+86- 531- 88024598

Address:7-702 Caizhi Central, 59 Gong Ye South Road, Jinan City,250101, P. R. China
Synasia Inc

Contact:17316303296

Address:240 Amboy Ave
Rayfull Holding Co., Ltd

Contact:+86-577-65618087-605

Address:Room 402, Unit 4 Xinhu Bldg. Waitan Ruian City, Zhejiang China.
Chameleon Specialty Chemicals

Contact:+44 7958 511245

Address:PO Box 469, Manchester, UK

Relevant to this article

Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease

Doi:10.1021/jm960603e
(1996)
A new and efficient synthesis of (-)-indolizidine 167B by tandem metathesis

Doi:10.1016/S0040-4039(02)01534-4
(2002)
Photochemical reactions of thiobenzamides bearing an allylic substituent on the nitrogen atom: Double-bond migration via tandem 1,4- And 1,6-hydrogen transfer

Doi:10.1039/a700247e
(1997)
A novel concept in combinatorial chemistry in solution with the advantages of solid-phase synthesis: Formation of N-betaines by multicomponent domino reactions

Doi:10.1002/1521-3773(20010302)40:5<903::AID-ANIE903>3.0.CO;2-7
(2001)
Nickel-catalyzed oxidative coupling reactions of two different terminal alkynes using O₂ as the oxidant at room temperature: Facile syntheses of unsymmetric 1,3-diynes

Doi:10.1021/ol8027863
(2009)
Synthesis of chalcone derivatives on steroidal framework and their anticancer activities

Doi:10.1016/j.steroids.2007.07.012
(2007)

Article Doi