Angewandte Chemie - International Edition p. 2700 - 2703 (2008)
Update date:2022-09-26
Topics:
Buchini, Sabrina
Buschiazzo, Alejandro
Withers, Stephen G.
(Chemical Equation Presented) A substitution for inhibition: The incorporation of anaryl substituent at C9 of 3-fluorosialyl fluorides provides specificity and dramatically slows the reactivation of the glycosylphosphatidylinositol-anchored surface protein Trypanosoma cruzi trans-sialidase (TcTS) by transglycosylation (see picture). X-ray crystallographic analysis of the trapped intermediate has provided a structural rationale for this behavior.
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Doi:10.1021/ol800544a
(2008)Doi:10.1080/00268977300101841
(1973)Doi:10.1021/jo00372a031
(1986)Doi:10.1021/jo01363a600
(1957)Doi:10.1021/ja00760a050
(1972)Doi:10.1039/c0cc02865g
(2010)
