A combined in silico/in vitro approach unveils common molecular requirements for efficient BVDV RdRp binding of linear aromatic N-polycyclic systems

DOI: 10.1016/j.ejmech.2016.03.080

Source and publish data:

European Journal of Medicinal Chemistry p. 321 - 334 (2016)

Update date:2022-08-04

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Authors:

Carta Carta

Briguglio

Piras Piras

Corona Corona

Ibba Ibba

Laurini Laurini

Fermeglia

Pricl Pricl

Desideri

Atzori Atzori

La Colla

Collu Collu

Delogu Delogu

Loddo Loddo

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Article abstract of DOI:10.1016/j.ejmech.2016.03.080

In this work, we present and discuss a comprehensive set of both newly and previously synthesized compounds belonging to 5 distinct molecular classes of linear aromatic N-polycyclic systems that efficiently inhibits bovine viral diarrhea virus (BVDV) infe

Full text of DOI:10.1016/j.ejmech.2016.03.080

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