Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase

DOI: 10.1016/j.bmc.2013.01.024

Source and publish data:

Bioorganic and Medicinal Chemistry p. 2007 - 2017 (2013)

Update date:2022-09-26

Topics:

Authors:

Venkatraman, Srikanth

Velazquez, Francisco

Gavalas, Stephen

Wu, Wanli

Chen, Kevin X.

Nair, Anilkumar G.

Bennett, Frank

Huang, Yuhua

Pinto, Patrick

Jiang, Yueheng

Selyutin, Oleg

Vibulbhan, Bancha

Zeng, Qingbei

Lesburg, Charles

Duca, Jose

Huang, Hsueh-Cheng

Agrawal, Sony

Jiang, Chuan-Kui

Ferrari, Eric

Li, Cheng

Kozlowski, Joseph

Rosenblum, Stuart

Shih, Neng-Yang

Njoroge, F. George

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Article abstract of DOI:10.1016/j.bmc.2013.01.024

The characterization of HCV genome has identified various vital functional proteins involved in the life cycle of hepatitis C virus. This has resulted in many novel enzymatic targets that are potential for development of therapeutic agents. The HCV RNA de

Full text of DOI:10.1016/j.bmc.2013.01.024

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