Journal of Medicinal Chemistry p. 245 - 248 (1985)
Update date:2022-08-03
Topics:
DeMarinis, Robert M.
Lavanchy, Patricia
Hieble, J, Paul
Jim, Kam F.
Matthews, William D.
N-<2-hydroxy-5-<2-(methylamino)ethyl>phenyl>methanesulfonamide (SKandF 102652) has been prepared and characterized pharmacologically.It is a potent agonist with an EC50 of 25 nM at α1-adrenoceptors as determined in the isolated perfused rabbit
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