Journal of Medicinal Chemistry p. 121 - 131 (1987)
Update date:2022-08-05
Topics:
Showalter
Johnson
Hoftiezer
Turner
Werbel
Leopold
Shillis
Jackson
Elslager
Chromophore modification of the anthracenediones related to mitoxantrone in an attempt to provide agents with diminished or no cardiotoxicity has resulted in a novel class of DNA binders, the anthrapyrazoles. Their synthesis was carried out by a two-stage
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