Nucleosides. 139. Synthesis and Anticytomegalovirus and Antiherpes Simplex Virus Activity of 5'-Modified Analogues of 2'-Fluoroarabinosylpyrimidine Nucleosides

DOI: 10.1021/jm00384a041

Source and publish data:

Journal of Medicinal Chemistry p. 226 - 229 (1987)

Update date:2022-07-30

Topics:

Authors:

Harada, Kazuho

Matulic-Adamic, Jasenka

Price, Richard W.

Schinazi, Raymond F.

Watanabe, Kyoichi A.

Fox, Jack J.

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Article abstract of DOI:10.1021/jm00384a041

In order to determine if modification of the 5'-position reduces or abolishes the antiviral activity of 2'-fluoro-5-iodo-ara-C (FIAC), 2'-fluoro-5-iodo-ara-U (FIAU), or 2'-fluoro-5-methyl-ara-U (FMAU) against human cytomegalovirus (HCMV) and herpes simple

Full text of DOI:10.1021/jm00384a041

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