Synthesis of new OBAN's and further studies on positioning of the catalytic group.

DOI: 10.1039/b403652b

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Organic and biomolecular chemistry p. 1901 - 1907 (2004)

Update date:2022-09-26

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Authors:

Astroem, Hans

Stroemberg, Roger

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Article abstract of DOI:10.1039/b403652b

Two new zinc ion dependent oligonucleotide based artificial nucleases (OBAN's) have been synthesized. These consist of 2'-O-methyl modified RNA oligomers conjugated to 5-amino-2,9-dimethylphenanthroline (neocuproine)via a urea linker. OBAN 4 carries the c

Full text of DOI:10.1039/b403652b

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