ETUDES DE LIGNANES 7 - SYNTHESES TOTALES DES (+-)-α ET -β-CONIDENDRINES ET DES METHYL (+-)-α ET -β-CONIDENDRALS

Article abstract of DOI:10.1016/S0040-4020(01)87617-1

Michael addition of the carbanion of the dithian 8 on butenolide, followed by alkylation with the benzylic bromide 11 and regeneration of the ketonic carbonyl group, gave the α,β-disubstituted lactone 13.Reduction of the ketonic carbonyl of the latter usi