Asymmetric synthesis. VIII. Biogenetically patterned approach to the chiral total synthesis of (-)-pumiliotoxin-C

Article abstract of DOI:10.1016/S0040-4039(00)84315-4

(-)-Pumiliotoxin-C and the (+)-9,10-trans isomer 10 were prepared in six steps from the chiral (+)-2-cyano-6-oxazolopiperidine synthon 3.