Tetrahedron Letters p. 5840 - 5842 (2008)
Update date:2022-07-29
Topics:
Kalusa, Andrew
Chessum, Nicola
Jones, Keith
A practical and efficient three step synthetic route to 2,3-diaryl (3H)-quinazolin-4-ones has been developed. The key step involves microwave-assisted condensation of an imidoyl chloride with an aryl amine. This methodology affords the products cleanly and in high yields.
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