EINE NEUE SYNTHESE VON VINBLASTIN-DERIVATEN V. KONZEPT UND UNTERSUCHUNGEN ZUR SYNTHESE VON 20'-DESETHYL-20'-DESOXY-C'-HOMOVINBLASTIN-OCTAHYDRO-3H-AZECINOINDOL-DERIVATE

DOI: 10.1016/S0040-4020(01)86686-2

Source and publish data:

Tetrahedron p. 1211 - 1220 (1990)

Update date:2022-07-31

Topics: SYNTHESE

Authors:

Schill, Gottfried

Priester, Claus Ulrich

Windhoevel, Udo Frank

Fritz, Hans

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Article abstract of DOI:10.1016/S0040-4020(01)86686-2

A concept for the synthesis of C'-homovinblastine derivative 1 is presented in which the azecinoindole derivative 3 and the bicyclic lactam 5 are key intermediates.Starting from tryptamine, the synthesis of these two intermediates is described.In addition

Full text of DOI:10.1016/S0040-4020(01)86686-2

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