Synthesis and antiarrhythmic activity of novel 3-alkyl-1-[ω-[4-[(alkylsulfonyl)amino]phenyl]-ω-hydroxyalkyl]-1H-im dazolium salts and related compounds

DOI: 10.1021/jm00395a021

Source and publish data:

Journal of Medicinal Chemistry p. 2303 - 2309 (1987)

Update date:2022-08-03

Topics:

Authors:

Lis Lis

Davey Davey

Morgan Jr.

Lumma Jr.

Wohl Wohl

Jain Jain

Wan Wan

Argentieri

Sullivan

Cantor Cantor

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Article abstract of DOI:10.1021/jm00395a021

Novel analogues of the class III antiarrhythmic agent 1-[2-hydroxy-2-[4-[(methylsulfonyl)amino]phenyl]ethyl]-3-methyl-1H-im dazolium chloride, 1 (CK-1649), were prepared and investigated for their class III electrophysiological activity on isolated canine

Full text of DOI:10.1021/jm00395a021

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Product name:Methanesulfonamide, N-[4-(4-chloro-1-oxobutyl)phenyl]-

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