
Tetrahedron Letters p. 2463 - 2464 (1986)
Update date:2022-07-29
Topics: Monitor the reaction Characterize the product Optimize Reaction Conditions Prepare the Reaction Mixture
Hanamoto, Takeshi
Katsuki, Tsutomu
Yamaguchi, Masaru
Formation of the quarternary asymmetric center by double alkylation of cyanoacetamide enolate bearing trans-2,5-bis(methoxymethoxymethyl)pyrrolidine moiety as a chiral auxiliary, was carried out with high diastereoselectivity.
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(1985)