Novel Synthesis of 2-Aminothiophenes via Iodoiminothiolactonization of γ,δ-Unsaturated Secondary Thioamides

DOI: 10.1039/c39860001671

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1671 (1986)

Update date:2022-08-03

Topics: Characterization Regio-selective Chemo-selective Spectral data Thioamide Synthon Solvent Ring closure Workup and Isolation Reaction Conditions Amino Group Introduction

Authors:

Takahata, Hiroki

Moriyama, Keiko

Moruyama, Mihoko

Yamazaki, Takao

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Article abstract of DOI:10.1039/c39860001671

Iodine-induced cyclization of γ,δ-unsaturated secondary thioamides proceeds regio- and chemo-selectively, providing, after elaboration, 2-aminothiophenes.

Full text of DOI:10.1039/c39860001671

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