Grignard cross-coupling amenable to large scale production of α-fluorostyryl and α-fluorovinylthiophenes

DOI: 10.1021/jo801647x

Source and publish data:

Journal of Organic Chemistry p. 9775 - 9777 (2008)

Update date:2022-08-03

Topics:

Authors:

Qiu, Jian

Gyorokos, Albert

Tarasow, Theodore M.

Guiles, Joseph

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Article abstract of DOI:10.1021/jo801647x

(Chemical Equation Presented) An efficient nickel-catalyzed Kumada-Corriu cross coupling enabled the introduction of an α-fluorovinyl functionality with excellent conversion and specificity.

Full text of DOI:10.1021/jo801647x

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