Synthesis of Angiotensin II Antagonists with Variations in Position 5

DOI: 10.1021/jm00393a006

Source and publish data:

Journal of Medicinal Chemistry p. 1719 - 1724 (1987)

Update date:2022-07-29

Topics: Synthesis ANGIOTENSIN II Antagonists Variations Experimental

Authors:

Nyeki, Olga

Szalay, Katalin Sz.

Kisfaludy, Lajos

Karpati, Egon

Szporny, Laszlo

et al. et al.

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Article abstract of DOI:10.1021/jm00393a006

Six angiotensin II antagonists containing cyclohexylglycine (Chg) or cyclopentylglycine (Cpg) in position 5 were synthesized by stepwise elongation in solution, using the pentafluorophenyl ester method.The influence of substitution on the inhibitory prope

Full text of DOI:10.1021/jm00393a006

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