Synthesis of Angiotensin II Antagonists with Variations in Position 5

DOI: 10.1021/jm00393a006

Source and publish data:

Journal of Medicinal Chemistry p. 1719 - 1724 (1987)

Update date:2022-07-29

Topics: Synthesis ANGIOTENSIN II Antagonists Variations Experimental

Authors:

Nyeki, Olga

Szalay, Katalin Sz.

Kisfaludy, Lajos

Karpati, Egon

Szporny, Laszlo

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00393a006

Six angiotensin II antagonists containing cyclohexylglycine (Chg) or cyclopentylglycine (Cpg) in position 5 were synthesized by stepwise elongation in solution, using the pentafluorophenyl ester method.The influence of substitution on the inhibitory prope

Full text of DOI:10.1021/jm00393a006

Products guided by the article

Product name:Boc-Arg(NO₂)-Val-Tyr(Bzl)-Chg-His(Dnp)-Pro-Lac-OBzl

Cas No:109183-80-4

R&D Labs maybe for 109183-80-4

puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road
Jiaxing Barton Chemicals

website:http://www.chinabarton.com

Contact:+86-573-82719618

Address:No. 162 Fumin Road, Honghe Town,
Jinan Jinguilin Chemical Co.,Ltd

Contact:+86-531-81188412

Address:3rd floor of Torch Building, Huanyuan Rd, City of Jinan
Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China
Hubei Vanz Pharm Co.,Ltd

website:http://www.vanzpharm.com/en/index.html

Contact:86-27-84492310

Address:FANHU INDUSTRY PARK

Relevant to this article

Evidence for partially bound states in cooperative molecular recognition interfaces

Doi:10.1021/ja803434z
(2008)
Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs

Doi:10.1021/acs.jmedchem.9b01172
(2020)
Regioselective synthesis of 2-(arylthio)benzoates by the first catalytic [3+3] cyclocondensations of 3-(arylthio)-1-(trimethylsilyloxy)-1,3-butadienes with 1,1,3,3-tetramethoxypropane

Doi:10.1055/s-0028-1083516
(2008)
Formation of cyclic sulfonamides via an unusual 8-endo-trig Heck olefination reaction

Doi:10.1016/j.tetlet.2008.10.004
(2008)
New synthesis of 1,3-diaryl-4-nitro-1-butanones by microwave-promoted Michael addition of nitromethane to chalcones without solvent

Doi:10.3184/030823407X266199
(2007)
Phenylselenium Trichloride in Organic Synthesis. Reaction with Unsaturated Compounds. Preparation of Vinylic Chlorides via Selenoxide Elimination

Doi:10.1021/jo00227a026
(1987)

Article Doi